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Record W4415949221 · doi:10.1002/dev.70101

The Development of Lateralized Brain Oscillations in Infants: Lessons From Autism

2025· article· en· W4415949221 on OpenAlexafffund
Gabriel Blanco‐Gomez, Christian O’Reilly, Sara Jane Webb, Mayada Elsabbagh

Bibliographic record

VenueDevelopmental Psychobiology · 2025
Typearticle
Languageen
FieldNeuroscience
TopicHemispheric Asymmetry in Neuroscience
Canadian institutionsMcGill UniversityMontreal Neurological Institute and Hospital
FundersMedical Research CouncilFonds de Recherche du Québec - SantéNational Institutes of HealthFonds de recherche du QuébecFondation Brain Canada
KeywordsLateralization of brain functionAutismAutism spectrum disorderBrain asymmetryElectroencephalographyNeurodevelopmental disorderLanguage developmentDevelopmental disorder

Abstract

fetched live from OpenAlex

The lateralization of brain activity is important for language processing and attention, and atypical patterns of lateralization have been linked to many neurodevelopmental disorders, including autism spectrum disorder (ASD). However, the developmental timing of these patterns and their relationship to emerging ASD characteristics are unclear. In this study, we used data from EEG-IP (International Infant EEG Data Integration Platform), a longitudinal cohort bringing together infants at elevated likelihood for ASD and age-equivalent controls across two sites. We examined brain lateralization in electroencephalography (EEG) power during the first year of life. Overall, we identified differences in gamma band lateralization in infants later diagnosed with ASD at 12 months but not at 6 months. Additionally, we observed a shift from high left gamma band asymmetry at 6 months toward more symmetry by 12 months in our control group, highlighting between-group differences in developmental trajectories in brain oscillatory activity. We found key differences in the lateralization across groups in brain regions within the auditory network, which is thought to be important for language learning. Overall, examining the developmental trajectories of lateralization is a crucial step toward creating more accurate models of brain development and better understanding the underlying mechanisms of neurodevelopmental disorders.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.583
Threshold uncertainty score0.573

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.348
Teacher spread0.311 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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