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Record W4415971713 · doi:10.1101/2025.11.03.25339450

Patient-Level Stroke Outcomes Following Linkage of a Statewide Stroke Registry to Administrative Claims Data

2025· preprint· W4415971713 on OpenAlexaboutno aff
Raed Hailat, Michael P. Thompson, Adrienne Nickles, J. Adam Oostema, Gustavo de los Campos, Mathew J. Reeves

Bibliographic record

VenuemedRxiv · 2025
Typepreprint
Language
FieldMedicine
TopicAcute Ischemic Stroke Management
Canadian institutionsnot available
Fundersnot available
KeywordsStroke (engine)Acute strokeCohortRehabilitationRecord linkageCohort studyHealth careQuarter (Canadian coin)

Abstract

fetched live from OpenAlex

Background Collection of patient-level outcomes data following hospital discharge is challenging for stroke registries. Data linkage to administrative claims data is a potential solution to obtain outcomes data. We aimed to generate data on 30-day, 90-day and 1-year outcome events following hospitalization for stroke using linked data in Michigan. Methods We probabilistically linked clinical data from a 5-year cohort (2016-2020) of all index acute stroke discharges (ICD-10 I61-I63) from 31 hospitals participating in Michigan’s Acute Stroke program (MiSP) to a representative statewide multi-payer claims database. We used the linked data to generate data on 30-day, 90-day, and 1-year event rates including hospital readmissions, stroke recurrence, post-acute care services (i.e., facility-based rehabilitation and home health), and out-patient visits. Mortality data was only available for Medicare fee-for-service beneficiaries. Outcomes were stratified by age, race, stroke type, and stroke severity. Results Of the 46,330 MiSP stroke discharges, 23,918 (51.6%) were linked to the claims database. Readmission and stroke recurrence rates were 14.1% and 3.3%, respectively, at 30 days, increasing to 42.2% and 8.3% at one year. By 30 days about a quarter of subjects had used facility-based rehab and another quarter had used home health; home health utilization increased to 44.7% by one year. At all time points Black patients had significantly higher readmission rates compared to whites, but higher stroke recurrence rates were only observed at the 1-year mark. At 30 days, utilization of post-acute care services did not differ by race, but utilization rates were significantly higher in Blacks at 90 days and one year. In contrast utilization of outpatient services was significantly higher among White patients at all time points. Conclusions Linkage between acute stroke registry and claims data provides an important source of surveillance data for stroke outcomes up to 1-year post discharge. This data allows for real-time monitoring of healthcare outcomes and potentially leads to interventions to improve stroke care.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.014
metaresearch head score (Gemma)0.046
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.015
Threshold uncertainty score0.072

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0140.046
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0030.006
Science and technology studies0.0010.000
Scholarly communication0.0020.001
Open science0.0010.003
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.095
GPT teacher head0.364
Teacher spread0.269 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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