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Record W4415983464 · doi:10.4208/cicp.oa-2024-0156

RBMD: A Molecular Dynamics Package Enabling to Simulate 10 Million All-Atom Particles in a Single Graphics Processing Unit

2025· article· W4415983464 on OpenAlexaff
Weihang Gao, Teng Zhao, Yongfa Guo, Jiuyang Liang, Maoying Luo, Zedong Luo, Wei Qin, Yichao Wang, Qi Zhou, Shi Jin, Zhenli Xu

Bibliographic record

VenueCommunications in Computational Physics · 2025
Typearticle
Language
FieldBiochemistry, Genetics and Molecular Biology
TopicProtein Structure and Dynamics
Canadian institutionsArtificial Intelligence in Medicine (Canada)
Fundersnot available
KeywordsVerlet integrationMolecular dynamicsBenchmark (surveying)GraphicsGraphics processing unitFast Fourier transformCUDAConstruct (python library)

Abstract

fetched live from OpenAlex

This paper introduces a random-batch molecular dynamics (RBMD) package for simulations of particle systems at the nano/micro scale. Different from existing packages, the RBMD uses random batch methods for nonbonded interactions of particle systems. The long-range part of Coulomb interactions is calculated in Fourier space by the random batch Ewald algorithm, which achieves linear complexity and superscalability, surpassing classical lattice-based Ewald methods. For the short-range part, the random batch list algorithm is used to construct neighbor lists, significantly reducing computational and memory costs. The RBMD is implemented on GPU-CPU heterogeneous architectures, with classical force fields for all-atom systems. Benchmark systems are used to validate the accuracy and performance of the package. Comparison with the particle-particle particle-mesh and the Verlet list methods in the LAMMPS package is performed on three different NVIDIA GPUs, demonstrating high efficiency of the RBMD on heterogeneous architectures. Our results also show that the RBMD enables simulations on a single GPU with a CPU core up to 10 million particles. Typically, for systems of one million particles, the RBMD allows simulating all-atom systems with a high efficiency of 8.20 ms per step, demonstrating the attractive feature for running large-scale simulations of practical applications on a desktop machine.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.022
Threshold uncertainty score0.073

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0040.001
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0220.008

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.327
Teacher spread0.300 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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