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Record W4415990284 · doi:10.3390/ani15223230

MiRNAs in Poultry Health and Production: Progress and Challenges

2025· review· en· W4415990284 on OpenAlexaff
Thanh Van Nguyen, Tan Hy Tat, Duy Ngoc

Bibliographic record

VenueAnimals · 2025
Typereview
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMicroRNA in disease regulation
Canadian institutionsDalhousie University
Fundersnot available
KeywordsmicroRNAIdentification (biology)Mechanism (biology)TraitGenomeDisease

Abstract

fetched live from OpenAlex

MicroRNAs (miRNAs) are small, non-coding RNA molecules that play crucial roles in the regulation of gene expression. In poultry, miRNAs have emerged as significant regulators of various biological processes, such as growth, development, immune response, and disease resistance in humans, plants, and animals. Recent studies have identified numerous miRNAs in different poultry species (chickens, geese, turkeys, quails, and ducks) and have elucidated their roles in various economically important traits in these species. This review aims to provide a comprehensive overview of the progress made in understanding the functions and mechanisms of miRNAs in poultry as well as the challenges faced in this field. Firstly, an overview of progress in the identification and validation of miRNAs in each species is provided. Then, specific roles of miRNAs in different classes of phenotypic traits are presented. Finally, the challenges and impacts of key technologies and methods, including artificial intelligence, genome editing, and single-cell sequencing, are discussed. From state-of-the-art research on miRNA functions across different trait classes to up-to-date technology trends, this review provides a comprehensive picture of miRNAs in poultry, which might open up new research and application possibilities.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.002
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.050
GPT teacher head0.352
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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