Predicting and improving diagnosis of tuberculosis outcomes in South Africa using machine learning techniques
Bibliographic record
Abstract
The Ministry of Health and Social Welfare of South Africa has made significant efforts to combat tuberculosis (TB), guided by the National Strategic Plan for addressing HIV, STIs, and TB. However, progress in preventing and eradicating TB has been seriously hindered by reliance on ineffective diagnostic methods. This study aimed to predict and improve TB diagnosis in South Africa using machine learning techniques. Data from the National Income Dynamics Survey, conducted by the Southern African Labour and Development Research Units, were analyzed. The dataset underwent a 70:30 train-test split for Random Forest (RF), Decision Trees (DTs), Support Vector Machines (SVMs), Gradient Boosting Machines (GBMs), Artificial Neural Networks (ANNs), and Logistic Regression (LR). Hyperparameter tuning and impurity-based measures were employed to rank variable importance. RF achieved 87.50% sensitivity and an F1-score of 92.5%. DT achieved a sensitivity of 90.92% and an F1-score of 93.01%. ANN yielded 81.72% sensitivity and an F1-score of 87.53%. SGBMs showed 91.32% sensitivity and 94.55% F1-score. SVMs showed 90.03% sensitivity and 97.72% F1-score. LR achieved a sensitivity of 96.55% and an F1-score of 96.80%. Machine Learning (ML) techniques, with accuracy rates of more than 80% present a significant opportunity for enhancing TB prediction and diagnosis in South Africa. This predictive technique may be beneficial in resource-constrained settings, including those in sub-Saharan Africa.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.007 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".