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Record W4416056663 · doi:10.1021/acs.jchemed.5c00456

Is That a Peak? A Course-Based Research Experience That Has Students Performing a Nontargeted Analysis of Dust and Consumer Products

2025· article· en· W4416056663 on OpenAlexafffund
Selene J. Kutarna, William D. Fahy, Jessica C. D’eon

Bibliographic record

VenueJournal of Chemical Education · 2025
Typearticle
Languageen
FieldChemistry
TopicVarious Chemistry Research Topics
Canadian institutionsUniversity of Toronto
FundersUniversity of Toronto
KeywordsCoding (social sciences)Component (thermodynamics)Data collectionSample (material)Field (mathematics)Product (mathematics)

Abstract

fetched live from OpenAlex

Modern analytical environmental chemistry has increasingly moved away from traditional targeted chemical monitoring and toward a more nontargeted, big data approach. In this activity, students use freely available software to perform a nontargeted analysis of high-resolution mass spectrometry data from real indoor dust and consumer product samples. Students collect supporting evidence within the dataset to reduce uncertainty and contextualize their results within the field of environmental chemistry using primary literature. There is also an emphasis on data analysis as a core component of modern chemical research. This activity was delivered twice over the course of two years, first online during the initial wave of COVID-19, then in person the subsequent year, whereupon R coding was introduced to semiautomate the detection of candidate compounds. Student feedback was strong, with 96% of students indicating moderate to high satisfaction with the research component of the activity after the second iteration. Sufficient resources and sample data are provided for instructors to deliver this activity without needing access to a high-resolution mass spectrometer.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.297
Threshold uncertainty score0.537

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.119
GPT teacher head0.433
Teacher spread0.315 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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