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Record W4416065919 · doi:10.1093/inteam/vjaf163

Canadian A.I. Removal Rate Estimator (CAIRRE): an artificial intelligence model to predict the removal of chemicals in secondary wastewater treatment plants

2025· article· en· W4416065919 on OpenAlexaffabout
Michael Beking, Jesse Shen, Shirley Anne Smyth

Bibliographic record

VenueIntegrated Environmental Assessment and Management · 2025
Typearticle
Languageen
FieldEnvironmental Science
TopicPharmaceutical and Antibiotic Environmental Impacts
Canadian institutionsEnvironment and Climate Change Canada
Fundersnot available
KeywordsEffluentSewage treatmentSecondary treatmentEstimatorWastewaterPredictive modelling

Abstract

fetched live from OpenAlex

Understanding the removal of a chemical in a wastewater treatment plant (WWTP) is important when performing chemical risk assessments. Chemicals undergoing assessment often have limited experimental measurements of physicochemical properties, biodegradation rates, and WWTP removal efficiencies. Models available to risk assessors to predict WWTP removal efficiencies are best used with high-quality input data and knowledge of plant conditions, information often unavailable when performing chemical risk assessments. In this work, we outline the development of the Canadian A.I. Removal Rate Estimator (CAIRRE), an artificial intelligence (A.I.) model suite designed to estimate removal efficiencies from secondary WWTPs. CAIRRE was trained on median experimental removal efficiencies for 161 chemicals across 59 secondary WWTPs in Canada, the USA (California), and various other locations curated from literature. The CAIRRE regression model has a validation Pearson R2 of 0.81 based on leave-one-out-validation (LOOV) results. When used to predict effluent concentrations for a test set containing 53 chemicals not seen during model training, CAIRRE was able to reproduce experimental observations with a Pearson R2 of 0.91. The CAIRRE model outperformed existing mechanistic and fugacity WWTP models which rely on physical-chemistry and biodegradation data provided by the user. This work demonstrates that the A.I. modeling approach taken in the development of CAIRRE is a promising strategy for predicting removal efficiencies of chemicals from secondary WWTPs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.338
Threshold uncertainty score0.681

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.004
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0030.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.300
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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