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Record W4416082255 · doi:10.1177/1753495x251391574

Management of sickle cell disease in pregnancy

2025· review· en· W4416082255 on OpenAlexaff
Tabea Sutter, Nadine Shehata, Kristine Matusiak, Ann Kinga Malinowski

Bibliographic record

VenueObstetric Medicine · 2025
Typereview
Languageen
FieldMedicine
TopicHemoglobinopathies and Related Disorders
Canadian institutionsThrombosis and Atherosclerosis Research InstituteUniversity of TorontoUniversity Health NetworkLunenfeld-Tanenbaum Research InstituteMount Sinai HospitalMcMaster University
Fundersnot available
KeywordsPregnancyDiseaseHemolysisAnemiaAdverse effectCellFetusMultidisciplinary approach

Abstract

fetched live from OpenAlex

Sickle cell disease (SCD) is the most common hemoglobinopathy, characterized by hemolysis and vaso-occlusion, resulting in multisystem disease. Pregnant patients with SCD may have preexisting organ dysfunction and SCD-specific pregnancy complications. Risk for adverse maternal or fetal outcomes is significantly elevated in SCD patients, and multidisciplinary care in a center with expertise is essential to minimize complications.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.717
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0010.003
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.304
Teacher spread0.283 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designOther design
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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