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Record W4416088470 · doi:10.56392/001c.146699

Longitudinal Evaluation of Delirium in Liver Transplant Recipients

2025· article· en· W4416088470 on OpenAlexaff
Jessica M. Ruck, Alexis A. Jefferis, Mayan Teles, Aura Teles, Sherif Helmy, Andrew M. Cameron, Karin J. Neufeld, Esther S. Oh, Elizabeth King

Bibliographic record

VenueDelirium · 2025
Typearticle
Languageen
FieldMedicine
TopicIntensive Care Unit Cognitive Disorders
Canadian institutionsMcMaster University
FundersNational Institute on AgingU.S. Department of Health and Human Services
KeywordsDeliriumLiver transplantationIntensive careOrganic mental disordersLongitudinal study

Abstract

fetched live from OpenAlex

Background: Increasingly shorter intensive care unit stays have limited the screening for delirium and therefore our understanding of delirium risk and characteristics in the modern liver transplant population. Objective: We sought to evaluate delirium prevalence in the intensive care unit, on the surgical floor, and overall during the liver transplant hospitalization. Methods: We enrolled 50 liver transplant recipients to receive daily delirium assessments using both the 4AT and either the Confusion Assessment Method (CAM) for the ICU or the CAM short form immediately pre-transplant and until the first of discharge or post-transplant day 14. We evaluated delirium prevalence in the ICU, on the surgical floor, and overall and visualized the daily mental status of recipients and cumulative incidence of delirium in this cohort. Results: Delirium was present in 58% of recipients, including 47% in the ICU and 43% on the surgical floor. Nine participants (31%) were captured as having delirium only on the surgical floor. Demographic and transplant characteristics were statistically similar between recipients with and without post-transplant delirium. Compared to recipients without post-transplant delirium, recipients with delirium had similar ICU length of stay [3 (2-5) vs. 2 (1-3) days, p=0.24] but significantly longer transplant hospitalization length of stay [16 (13-20) vs. 8 (8-13), p=0.004]. Conclusions: Delirium is highly prevalent among liver transplant recipients not only during their stay in the intensive care unit, but also on the surgical floor. These findings underscore the importance of continuing routine assessment for delirium on liver transplant recipients after transfer to the surgical floor to optimize post-transplant care.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.331
Teacher spread0.289 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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