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Injection Considerations for Administering Endocrine Parenteral Therapies to Children

2025· article· en· W4416100227 on OpenAlexaff
Keisha Bird, Stewart R. Miller, Julianne McKernan, Irena Hozjan

Bibliographic record

VenueThe Open Nursing Journal · 2025
Typearticle
Languageen
FieldMedicine
TopicPediatric Pain Management Techniques
Canadian institutionsHospital for Sick Children
Fundersnot available
KeywordsDistractionCINAHLFeelingPediatric nursingCertificationEndocrine system

Abstract

fetched live from OpenAlex

Introduction Early diagnosis of chronic endocrine conditions requiring injectable treatment is common, and injections may cause children to experience uncomfortable feelings ( e.g ., pain and anxiety). No recent publications have comprehensively described good nursing practices for pediatric injections. This review identifies key factors that can facilitate improved injection techniques and ideal treatment options for children, with a focus on endocrine parenteral therapies. Methods PubMed, Embase, and CINAHL were searched. MeSH search terms included “child,” “injections/methods,” “pain/prevention and control,” “pain management/methods,” “patient positioning,” and “analgesic/therapeutic use.” Literature related to interventions pediatric nurses can implement to decrease injection-related discomfort and other treatment factors that can minimize injection-related pain was included. Results Nurses should build a strong rapport with the child and/or caregiver, as this can improve the expectations for the injection experience. Nurses can assist caregivers with selecting the most appropriate treatment and provide options that may reduce out-of-pocket costs. Before administering an injection, nurses should check the “Five Rights,” assess skin to select an appropriate injection site, and prepare skin for injection. Good injection techniques include: administration of room temperature medications, comforting positioning and holding of the child by the caregiver, distraction activities, and local anesthetic agents. In addition to using good pediatric injection techniques, nurses can partner with Certified Child Life Specialists when available to help alleviate the child’s anxiousness. Discussion Pediatric nurses benefit from a broad understanding of pediatric injection techniques. Conclusion Optimal pre-, during, and post-injection techniques, along with proper education and care, can reduce pain and anxiety in children, improve caregivers’ experiences, and prevent treatment delays.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.649
Threshold uncertainty score0.382

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.045
GPT teacher head0.391
Teacher spread0.346 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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