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P267 Assessment of the impact of nebuliser type on fugitive emissions in a treatment room when delivering inhaled medications

2025· article· W4416103130 on OpenAlexaff
Jason Suggett, L Clutterbuck, M. Nagel

Bibliographic record

Venuenot available
Typearticle
Language
FieldMedicine
TopicInhalation and Respiratory Drug Delivery
Canadian institutionsTrudell Medical International (Canada)
Fundersnot available
KeywordsFugitive emissionsSalbutamolCleanroomInhalationAir monitoringNebulizerAerosolization

Abstract

fetched live from OpenAlex

Rationale Nebulisers are widely used to deliver inhaled medications. Fugitive emissions are aerosols created by the nebuliser that are not inhaled by the patient. Fugitive emissions along with nebuliser exudate may potentially contain viral pathogens which can pose a risk to others in close proximity. A laboratory investigation was performed to assess the potential for exposure to fugitive emissions within a treatment room. Methods Fugitive emissions produced by 3 different nebuliser types (AeroEclipse* II BAN* Nebuliser -breath-actuated, NebuTech† HDN† breath-enhanced, and Aerogen† Ultra-vibrating mesh) were assessed using salbutamol as a tracer and simulating an adult receiving a nebuliser treatment. Aerosol filters attached to breathing simulators were positioned 0.8 and 2 meters away from the nebuliser to represent caregivers within the room. Collection areas were also established within the test room to measure the amount of fugitive emissions/exudate that may have reached the caregiver but were not inhaled. The mass of salbutamol recovered from filters and collection surfaces was analysed by HPLC. Results Total recovered emissions/exudate varied depending on the type of nebuliser used. The BAN* Nebuliser produced the lowest amount of fugitive emissions. The vibrating mesh nebuliser produced a significantly higher recovered amount directly below the nebuliser compared to the other two devices. The distance between the patient and the healthcare worker was not determined to be a significant factor in the amount of exposure to fugitive emissions. Conclusions Healthcare workers should be aware of the potential risks associated with fugitive emissions from nebulisers and ways to minimise exposure. The choice of nebuliser can significantly affect the amount of fugitive emissions and exudate produced in a treatment environment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.375
Teacher spread0.351 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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