MétaCan
Menu
Back to cohort
Record W4416148734 · doi:10.1136/flgastro-2025-103321

Sexually transmissible infections affecting the gastrointestinal tract: what gastroenterologists and hepatologists need to know

2025· article· en· W4416148734 on OpenAlexaff
Daniel Richardson, Holly Mitchell, Claire Jenkins, Lewis C. E. Mason, Michael Ewens, Lucy Rabuszko, Callum Chessell, Deborah Williams, Colin Fitzpatrick, Omar Kadhim Mohammed, Jason Zucker, Henry J.C. de Vries, Kate S. Baker

Bibliographic record

VenueFrontline Gastroenterology · 2025
Typearticle
Languageen
FieldImmunology and Microbiology
TopicParasites and Host Interactions
Canadian institutionsInstitute of Infection and Immunity
Fundersnot available
KeywordsMen who have sex with menShigellaGonorrheaSexually transmitted diseaseCampylobacterChlamydiaAnal cancerEnteric virusBacterial vaginosis

Abstract

fetched live from OpenAlex

Sexually transmissible gastrointestinal (enteric) infections cause oropharyngitis, hepatitis, enteritis, proctocolitis and anorectal disease, and can mimic neoplastic and inflammatory gastrointestinal disease. Sexually transmissible enteric infections are generally seen in men who have sex with men (MSM) due to sexual behaviours which risk faecal-oral transmission. Oropharyngeal and anorectal sexually transmitted infections (STIs) are transmitted via direct inoculation from oral and anal sexual behaviours. Shigella spp, Campylobacter spp, Salmonella spp, diarrhoeagenic Escherichia coli , Giardia duodenalis and Entamoeba histolytica are recognised sexually transmissible enteric faeco-oral pathogens in MSM. Neisseria gonorrhoeae , Chlamydia trachomatis, herpes simplex virus (HSV), Treponema pallidum subspecies pallidum (Syphilis), mpox and HSV cause sexually transmissible oropharyngeal and anorectal disease. Cryptosporidium, intestinal spirochaetosis , Blastocystis, Strongyloides stercoralis, Enterobius vermicularis and enteric viruses have infrequently been reported as sexually transmissible in MSM. Sexually transmissible enteric infections have increased in MSM over the past 35 years. Gastroenterologists and hepatologists do not generally enquire about sexual behaviours, but identifying sexually transmissible enteric infections is important due to high rates of bacterial antimicrobial resistance, and the additional management includes: bacterial antimicrobial susceptibility testing, testing for STIs/HIV, providing recommendations for sexual abstinence and partner notification; and onward referral to specialist sexual health clinics for sexual health prevention interventions. In this review, we highlight the STIs which can affect the gastrointestinal tract and provide some key management points for gastroenterologists and hepatologists.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.061
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.279
Teacher spread0.270 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueFrontline GastroenterologySame topicParasites and Host InteractionsFrench-language works237,207