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Record W4416193989 · doi:10.1111/jocd.70523

Safety and Tolerability of the 1440‐ and 1927‐nm Non‐Ablative Fractional Diode Laser System for Skin Resurfacing: A Review of Current Literature

2025· article· en· W4416193989 on OpenAlexfundno aff
Roy G. Geronemus, Jordan V. Wang, Abby Jacobson, Ellen S. Marmur, Kristel D. Polder

Bibliographic record

VenueJournal of Cosmetic Dermatology · 2025
Typearticle
Languageen
FieldMedicine
TopicDermatologic Treatments and Research
Canadian institutionsnot available
FundersBausch Health
KeywordsTolerabilityAblative caseDowntimeCurrent (fluid)LaserSafety profile

Abstract

fetched live from OpenAlex

BACKGROUND: Energy-based devices, such as lasers, provide effective treatments for skin resurfacing. Ablative fractional lasers have a higher risk of adverse events (AEs), like scarring and postinflammatory hyperpigmentation, particularly in patients with darker skin types, than non-ablative fractional lasers. The 1440- and 1927-nm non-ablative fractional diode laser (NFDL) system is indicated for use in dermatological procedures requiring the coagulation of soft tissue and for general skin resurfacing procedures. AIM: To help inform clinical decision-making about the dual 1440/1927-nm NFDL system, particularly for treating patients with diverse skin types who require safe and effective resurfacing treatments. METHODS: A PubMed search of literature was conducted to review safety and tolerability outcomes from clinical studies of 1440- and 1927-nm NFDL treatments. RESULTS: Expected skin reactions, including erythema, edema, and crusting, were mild to moderate and self-limited for concurrent and individual use of the 1440- and 1927-nm handpieces. Mild discomfort and heat sensation, which were also expected, indicated that treatment was well tolerated. Safety was also demonstrated in patients with skin of color, with no serious AEs. Levels of patient satisfaction were high. CONCLUSIONS: The dual 1440/1927-nm NFDL system is a safe and well-tolerated option for resurfacing of diverse skin types with minimal postprocedural downtime and reduced risk of AEs relative to ablative lasers.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.226
Threshold uncertainty score0.257

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.350
Teacher spread0.332 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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