Energetic shifts reflect survival likelihood in Anopheles gambiae
Bibliographic record
Abstract
Life history theory predicts that resource allocation adapts to ecological and evolutionary pressures. We investigated resource and energy in the malaria vector Anopheles gambiae following exposure to two stressors: blood meals and infection by the microsporidian Vavraia culicis. Our findings reveal the costs of blood-feeding and parasitism on longevity, highlighting trade-offs in lifetime protein, carbohydrate, and lipid reserves. Notably, shifts in carbohydrate-to-lipid ratios were associated with survival likelihood, with survivors exhibiting higher resource reserves and uniquely transitioning from carbohydrate to lipid utilisation, a pattern absent in non-survivors. This study emphasises the coevolutionary dynamics between hosts and parasites, highlighting how intrinsic and extrinsic factors shape host physiology. More broadly, our results underscore the importance of integrating host metabolic responses into ecological and epidemiological frameworks to enhance understanding of parasite transmission and survival strategies.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.002 | 0.001 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".