MétaCan
Menu
Back to cohort
Record W4416221386 · doi:10.1302/1358-992x.2025.13.148

INCREASED VERTEBRAL BODY TETHER TENSION RESULTS IN GREATER SPINAL GROWTH MODULATION

2025· article· en· W4416221386 on OpenAlexaff
Craig R. Louer, Ron El‐Hawary, Jennifer Hurry, Hui Nian, Christine L. Farnsworth, Christopher R. Bartley, Tracey P. Bastrom, Michael P. Kelly, Peter O. Newton, S. Parent, Vivek N. Upasani

Bibliographic record

VenueOrthopaedic Proceedings · 2025
Typearticle
Languageen
FieldMedicine
TopicScoliosis diagnosis and treatment
Canadian institutionsIzaak Walton Killam Health Centre
Fundersnot available
KeywordsVertebral bodyTension (geology)ScoliosisIdiopathic scoliosisRadiographyVertebraBody height

Abstract

fetched live from OpenAlex

Increased vertebral body tether (VBT) tension has been shown to increase spinal growth modulation in an in-vivo porcine model. However, this relationship has not been studied in growing children. The aim of this study was to compare vertebral growth between the tethered and untethered side of individual vertebral bodies with varying amounts of tether tension. A multicenter pediatric registry was queried for patients with idiopathic scoliosis who were treated with right-sided VBT, had intraoperative tension values, and 3D reconstructions from biplanar radiographs at the first postoperative (FE) and 2yr time points. Tension was recorded as ordinal values and grouped as No Tension, Slight-Moderate, Maximal. Custom Matlab code was used to calculate vertebral height (mm) on the concave (untethered) and convex (tethered) sides of each vertebra from T5-T12 (most consistently instrumented in this cohort). Generalized linear mixed models (with subject as a random factor and one interaction term between intervertebral tension and the vertebral level above the tensioned segment) were used to analyze the effect of tension on vertebral body growth over the postop period. Fifty-two subjects with 330 instrumented vertebral bodies met inclusion. Mean age was 12.5±1yrs; 47F, 5M. The majority were skeletally immature (23 open TRC, 29 Closed; 38 Risser 0, 6 Risser 1, 8 Risser 2-4; Proximal Femoral Maturity Index (PFMI) 2: 9, 3: 21, 4: 20, 5: 2). The average height change from FE to two years was 1.6±1.9mm on the concave side, 1.2±1.8mm on the convex, and 0.3±2.1mm of differential change (concave-convex). No difference was found in concave height change based on tension (p=0.2). On the convexity, greater tension resulted in less height change (all groups differed; p≤0.04). Greater differential growth was observed with maximal tension than with no tension (p In this cohort of largely skeletally immature patients treated with VBT, the amount of intervertebral tension applied intra-operatively had a significant impact on vertebral body growth over two years, with greater tension resulting in less convex-sided vertebral growth and greater differential growth between the concave and convex sides of the vertebra.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.017
Threshold uncertainty score0.697

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.275
Teacher spread0.258 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueOrthopaedic ProceedingsSame topicScoliosis diagnosis and treatmentFrench-language works237,207