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Record W4416227247 · doi:10.1002/cjce.70159

Development of a layers of protection incorporated inherent safety index for chemical processes

2025· article· en· W4416227247 on OpenAlexvenueno aff
Wei Pu, Abdul Aziz Abdul Raman, Mahar Diana Hamid, Xiaoming Gao, Archina Buthiyappan

Bibliographic record

VenueThe Canadian Journal of Chemical Engineering · 2025
Typearticle
Languageen
FieldDecision Sciences
TopicRisk and Safety Analysis
Canadian institutionsnot available
Fundersnot available
KeywordsInherent safetyProcess safetySAFERProcess (computing)HazardChemical safetyProcess safety managementRisk assessmentSystem safety

Abstract

fetched live from OpenAlex

Abstract To date, numerous inherent safety indices, tailored to different process design stages and hazards, have been proposed to assess the inherent safety of chemical processes. However, traditional inherent safety indices mainly focus on identifying and evaluating process hazards, with limited consideration of risk mitigation. This work develops an enhanced inherent safety index (EISI), which integrates risk reduction strategies (RRSs) within layers of protection (LOP) into the various hazard sub‐indices of the pioneering inherent safety index (ISI), thereby enabling a more comprehensive inherent safety assessment. According to the LOP framework, RRSs are identified for each sub‐index, with different scores assigned to reflect the relative effectiveness of each measure. A designed formula is used to calculate the value of EISI. The proposed index was applied to the acetic acid process as a case study. The results indicate that the safety level of the acetic acid process significantly improves when appropriate RRSs are incorporated. Based on a comparison of three distinct risk mitigation schemes, the EISI has been demonstrated to be practical for assessing the safety performance of chemical processes with control measures of varying priorities. The EISI provides stakeholders with a list of RRSs to address various process hazards during the design stage. It expands conventional inherent safety indices by incorporating risk mitigation elements, thereby facilitating industries in developing a comprehensive safer chemical process.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.216
Threshold uncertainty score0.345

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.044
GPT teacher head0.283
Teacher spread0.239 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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