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Record W4416244470 · doi:10.1002/clt2.70110

Key Predictors of Adherence to a Mobile Health App for Managing Chronic Spontaneous Urticaria

2025· article· en· W4416244470 on OpenAlexaff
Hugo Viegas, Bernardo Sousa‐Pinto, Rafael José Vieira, Aisté Ramanauskaité, Ellen Witte‐Händel, Ana M. Giménez‐Arnau, Carole Guillet, Claudio Alberto Salvador Parisi, Constance H. Katelaris, Daria Fomina, Désirée Larenas‐Linnemann, Jorge Sánchez, E. Hernández García, Hermenio Lima, Ігор Петрович Кайдашев, Iman Nasr, Isabel Ogueta Canales, Iván Chérrez-Ojeda, Jonathan A. Bernstein, Jonny Peter, José Ignacio Larco Sousa, Kanokvalai Kulthanan, Karsten Weller, Kiran Godse, Krzysztof Rutkowski, Lāsma Lapiņa, Laurence Bouillet, Luís Felipe Ensina, Margarida Gonçalo, Maria Staevska, Mariam Ali Yousuf Al‐Nesf, Markus Magerl, Martin Metz, Martijn B. A. van Doorn, Mary Anne R. Castor, Maryam Khoshkhui, Μichael Μakris, Michihiro Hide, Mohamed Abuzakouk, Mona Al‐Ahmad, Murat Türk, Natasa Teovska Mitrevska, Niall Conlon, Nicole Nojarov, Pavel Kolkhir, Philip H. Li, Ramzy Mohammed Ali, Rand Arnaout, Riccardo Asero, Sabine Altrichter, Simon Francis Thomsen, Young‐Min Ye, Zenon Brzoza, Zuotao Zhao, Torsten Zuberbier, Frank Siebenhaar, Emek Kocatürk, Sophia Neisinger

Bibliographic record

VenueClinical and Translational Allergy · 2025
Typearticle
Languageen
FieldMedicine
TopicUrticaria and Related Conditions
Canadian institutionsMcMaster University
FundersSanofi GenzymeBioCrystCelltrionSanofiAstraZenecaKuwait UniversityTaiho PharmaceuticalPfizer
KeywordsmHealthMobile appsKey (lock)ResidenceMEDLINEChronic diseaseMedication adherence

Abstract

fetched live from OpenAlex

BACKGROUND: Mobile health technologies may improve the management of chronic diseases, such as chronic spontaneous urticaria. However, effectiveness of mHealth tools largely depends on patient adherence, which can be influenced by various demographic, clinical, behavioural, psychosocial factors, and apps characteristics (appealing and simplicity of use). Understanding these adherence patterns is crucial for optimizing mHealth interventions. In this study, we aimed to assess adherence patterns associated to the use of CRUSE, a mHealth app designed for patients with CSU. METHODS: We assessed users of the CRUSE app with self-reported CSU or suggested by a physician. For each user, we evaluated the number of days they completed the CRUSE daily monitoring questionnaire (app adherence) within the first 3 months after installation. We constructed univariable and multivariable ordered beta regression models to identify predictors of 3-month adherence to the app. RESULTS: We analysed data from 2085 patients (66,114 days). Median adherence to the CRUSE app was of 22 days (24.4% of 90 days). In multivariable regression models, the variables more strongly associated with increased adherence to CRUSE included age (average increase = 0.16 percent points [pp] per additional year; 95% credible interval [CrI] = 0.08; 0.23 pp), male sex (average difference = 4.24 pp; 95% CrI = 1.77; 6.39 pp), being from a European country (average difference = 2.66 pp; 95% CrI = 0.59; 5.19 pp), and using monoclonal antibodies (average difference = 4.60 pp; 95% CrI = 2.26; 6.65 pp). CONCLUSIONS: Our findings suggest that age, male sex, residence in Europe, and the use of monoclonal antibodies are significant factors associated with increased adherence to the CRUSE app. These insights may help identify patient subgroups who would benefit most from mHealth support in managing CSU.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.441
Threshold uncertainty score0.284

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.348
Teacher spread0.322 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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