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Record W4416255920 · doi:10.1093/ije/dyaf192

Cohort Profile: Brazilian High-Risk Cohort for Mental Health Conditions (BHRC)

2025· article· en· W4416255920 on OpenAlexaff
Giovanni Abrahão Salum, Carina de Giusti, Laila Souza, Juliana Juk, Rafaela Alkmin da Costa, Luisa Sugaya, Arthur Caye, André Simioni, Paula B. Rocha, Gisele Gus Manfro, Lucas Toshio Ito, Francisco Da Silva, Igor Duarte, Nathália Bianchini Esper, Maurício Anés, Rodolfo Furlan Damiano, Theodore D Satterthwaite, Carolina Muniz Carvalho, Patrícia Bado, Maurício Scopel Hoffmann, Julia Schäfer, C Casella, Sara Evans‐Lacko, Carolina Ziebold, Rudi Rocha, André Zugman, Andrea Parolin Jackowski, Ary Gadelha, Marcelo Q. Hoexter, Clarice S. Madruga, Rodrigo Grassi‐Oliveira, Annamaria Cattaneo, Audrey R. Tyrka, Tomáš Paus, Daniel S. Pine, Ellen Leibenluft, Argyris Stringaris, Kathleen Merikangas, Michael P. Milham, Alexandre R. Franco, Marcos Santoro, João Ricardo Sato, Vanessa Ota, Guilherme V. Polanczyk, Jair de Jesus Mari, Rodrigo A. Bressan, Eurı́pedes Constantino Miguel, Luís Augusto Rohde, Síntia Belangero, Pedro Mário Pan

Bibliographic record

VenueInternational Journal of Epidemiology · 2025
Typearticle
Languageen
FieldMedicine
TopicBipolar Disorder and Treatment
Canadian institutionsUniversité de Montréal
FundersH2020 European Research CouncilMedical Research CouncilNational Institutes of HealthMinistério da SaúdeConselho Nacional de Desenvolvimento Científico e TecnológicoFundação de Amparo à Pesquisa do Estado de São Paulo
KeywordsCohortMental healthCohort studyEpidemiologyCohort effect

Abstract

fetched live from OpenAlex

The Brazilian High-Risk Cohort for Mental Health Conditions (BHRC), formerly the High-Risk Cohort Study for Psychiatric Disorders in Childhood (HRC) [1], was established to advance the understanding of the developmental trajectories of pediatric mental health conditions by integrating information about behaviors, genes, environments, and brain development. The BHRC has an accelerated school-based longitudinal design in which children born between 1996 and 2004 were recruited at school in 2009 and 2010 and assessed every 2–4 years. The BHRC is one of the few population neuroscience studies from a middle-income country, integrating in-depth clinical assessments with data on environmental influences, genetics, imaging, cognition, and ecological momentary assessment (EMA), among others [2]. The cohort was established as a collaborative effort among three Brazilian universities: Universidade de São Paulo, Universidade Federal do Rio Grande do Sul, and Universidade Federal de São Paulo. This was possible through a networking grant from the Brazilian Science and Technology Ministry, which created the National Institute of Developmental Psychiatry for Children and Adolescents (in Portuguese, “Instituto Nacional de Psiquiatria do Desenvolvimento para a Infância e Adolescência”). Participants were recruited at state-funded schools of two Brazilian metropolitan areas: Porto Alegre (South, 1.5 million inhabitants, metropolitan area 4.4 million inhabitants) and São Paulo (Southeast, 11.4 million inhabitants, metropolitan area 22.8 million inhabitants).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.181
Threshold uncertainty score0.361

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.003
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0060.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.397
Teacher spread0.375 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractno

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