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Record W4416273420 · doi:10.1016/j.jvacx.2025.100753

Factors associated with COVID-19 non-vaccination among children and adolescents with chronic health conditions in Canada: A national cross-sectional study

2025· article· en· W4416273420 on OpenAlexaffabout
Arlanna Pugh, Sailly Dave, Marwa Ebrahim, Julie Laroche

Bibliographic record

VenueVaccine X · 2025
Typearticle
Languageen
FieldSocial Sciences
TopicVaccine Coverage and Hesitancy
Canadian institutionsPublic Health Agency of Canada
Fundersnot available
KeywordsVaccinationLogistic regressionOddsOdds ratioAsthmaImmunizationPublic healthEl Niño

Abstract

fetched live from OpenAlex

COVID-19 vaccine rollout has prioritized high risk populations, including children with chronic health conditions (CHC), who are at greater risk of severe illness and hospitalization if infected. This study aims to identify the sociodemographic factors associated with COVID-19 non-vaccination among Canadian children with at least one CHC, and parental reasons for non-vaccination. The Childhood COVID-19 Immunization Coverage Survey is a nationally representative, cross-sectional survey of parents with children younger than 18 years old in Canada. Data was collected from April to July 2022 on COVID-19 immunization coverage and parental intentions to vaccinate their children. This study featured parents with children ages 5 to 17 years old who had at least one CHC. Unadjusted and adjusted weighted logistic regression models were built to explore factors of non-vaccination within this cohort. Of the 882 parents with children who have at least one CHC, 138 (16 %) reported that their child was unvaccinated against COVID-19. Children who were a visible minority (aOR: 2.66, 99 % CI: 2.48, 2.85) or who did not have asthma (aOR: 1.48, 99 % CI: 1.42–1.56) had greater odds of being unvaccinated, whereas adolescents 12–17 years old had lower odds (aOR: 0.10, 99 % CI: 0.09–0.11). Unvaccinated parents who were hesitant or refused to vaccinate their child cited vaccine safety (67.2 %), inadequate research on COVID-19 vaccines (57.7 %), and vaccine effectiveness (55.9 %) as their top 3 concerns on COVID-19 vaccination. Study findings may help inform policies and programs designed to address parental vaccine hesitancy and increase vaccination uptake especially among children of visible minority, low SES and/or children who do not have asthma, but have other CHCs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.019
Threshold uncertainty score0.091

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.002
Science and technology studies0.0020.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.328
Teacher spread0.307 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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