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Record W4416291370 · doi:10.1038/s42003-025-08954-4

Early but discontinued exposure to a language exerts lasting effects on white matter architecture in the brain

2025· article· en· W4416291370 on OpenAlexafffund
Élise B. Barbeau, Lara J. Pierce, Stephanie Deschamps, Shanna Kousaie, Annie C. Gilbert, Jen‐Kai Chen, Shari R. Baum, Denise Klein

Bibliographic record

VenueCommunications Biology · 2025
Typearticle
Languageen
FieldMedicine
TopicAdvanced Neuroimaging Techniques and Applications
Canadian institutionsYork UniversityMcGill UniversityCentre for Research on Brain Language and MusicMontreal Neurological Institute and Hospital
FundersNatural Sciences and Engineering Research Council of CanadaGovernment of CanadaCentre for Research on Brain, Language and Music
KeywordsMandarin ChineseArcuate fasciculusWhite matterCognitionNeuroscience of multilingualismLateralization of brain functionExpressive SuppressionNeuroimaging

Abstract

fetched live from OpenAlex

Language experiences influence later cognitive development, but how they shape brain organization remains unclear. We investigated four groups of participants who differed in their early linguistic environments: International Adoptees (IA) from China, who discontinued their first language (L1) Mandarin in the first two years of life and only speak French since adoption; L1-Mandarin speakers with early acquisition and continued use of French; L1-French speakers; and English-French bilinguals. We used diffusion-weighted imaging to explore group differences in two white-matter tracts in the brain that play a role in language processing, the arcuate fasciculus and superior longitudinal fasciculus. Our findings revealed that despite discontinuing Mandarin early in life, IA participants exhibited structural features resembling those of native Mandarin speakers, including smaller tract volumes in the left hemisphere and more balanced tract volumes across hemispheres. In contrast, English-French bilingual and L1-French groups exhibited similar white-matter characteristics, which were distinct from the two tone-language exposed groups, suggesting a structural organization specific to tonal language experience, and not bilingualism in general.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.367
Teacher spread0.338 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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