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Record W4416291556 · doi:10.1038/s41746-025-02032-z

EVA-X: a foundation model for general chest x-ray analysis with self-supervised learning

2025· article· en· W4416291556 on OpenAlexaff
Jingfeng Yao, Xinggang Wang, Yuehao Song, Huangxuan Zhao, Jun Ma, Yajie Chen, Wenyu Liu

Bibliographic record

Venuenpj Digital Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicCOVID-19 diagnosis using AI
Canadian institutionsVector InstituteUniversity of TorontoUniversity Health Network
FundersNational Natural Science Foundation of China
KeywordsGeneralizationDomain (mathematical analysis)Medical imagingFoundation (evidence)AnnotationImage (mathematics)Medical diagnosis

Abstract

fetched live from OpenAlex

Artificial intelligence analysis methods for chest X-ray images are limited by insufficient annotation data and varying levels of annotation, resulting in weak generalization ability and difficulty in clinical dissemination. Here, we present EVA-X, an innovative foundational model based on X-ray images with broad applicability. EVA-X uses a self-supervised learning method capable of capturing both semantic and geometric information from unlabeled images for universal X-ray image representation. It has demonstrated exceptional performance in chest disease analysis and localization, becoming a model capable of spanning over 20 different chest pathologies and achieving leading results in over 11 different pathology detection tasks. Additionally, EVA-X significantly reduces the burden of data annotation in the medical AI field, showcasing strong potential in the domain of few-shot learning. The emergence of EVA-X will greatly propel the development and application of foundational medical models, leading to potential improvements in future medical research and clinical practice.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.698
Threshold uncertainty score0.824

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.321
Teacher spread0.295 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2025
Admission routes1
Has abstractyes

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