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Record W4416344801 · doi:10.1016/j.xnsj.2025.100825

The future is now: How AI is reshaping spine care

2025· article· en· W4416344801 on OpenAlexaff
Eric J. Muehlbauer, Mohammed Ali Alvi, David J. Kennedy, Michael G. Fehlings

Bibliographic record

VenueNorth American Spine Society Journal (NASSJ) · 2025
Typearticle
Languageen
FieldMedicine
TopicSpine and Intervertebral Disc Pathology
Canadian institutionsToronto Western HospitalUniversity Health NetworkCanada Research ChairsUniversity of Toronto
Fundersnot available
KeywordsSPINE (molecular biology)Health carePatient careMEDLINEField (mathematics)

Abstract

fetched live from OpenAlex

Introduction: Artificial intelligence (AI) is rapidly reshaping spinal care, transitioning from experimental algorithms to operational tools embedded in clinical workflows. This narrative review explores the evolving role of AI across the spine care continuum, including diagnostic imaging, surgical planning, intraoperative navigation, predictive analytics, and digital therapeutics. Methods: Using a mixed-methods approach, we synthesized insights from peer-reviewed literature, regulatory documents, press releases, and grey sources published between 2017 and 2025. Results: AI-enabled imaging platforms now assist in detecting spinal pathologies and extracting quantitative metrics such as disc heights and Cobb angles, improving diagnostic consistency and reducing inter-rater variability. In surgical planning, decision-support systems and robotics-integrated platforms offer personalized guidance and enhanced precision. Intraoperative tools using 2D-3D fusion and volumetric reconstruction are enabling hardware-light navigation, particularly in ambulatory settings. Predictive models for survival, reoperation risk, and patient-reported outcomes are emerging, though external validation remains limited.Digital therapeutics and wearable technologies are expanding the reach of spine care beyond the clinic, offering scalable solutions for rehabilitation and postoperative monitoring. Meanwhile, regulatory and legal frameworks are evolving to address transparency, data governance, and intellectual property concerns. Recent FDA guidance and landmark legal cases underscore the need for disciplined collaboration and responsible deployment. Conclusions: AI in spine care is no longer theoretical and is operational. Its integration promises enhanced precision, efficiency, and personalization, but also demands rigorous validation and ethical oversight. This review highlights the multifaceted impact of AI and calls for continued alignment between clinicians, developers, and regulators to ensure safe, equitable, and sustainable innovation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.360
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.001
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.298
Teacher spread0.290 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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