MétaCan
Menu
Back to cohort
Record W4416392537 · doi:10.3390/diagnostics15222920

Normative Data for the Montreal Cognitive Assessment (MoCA) in Mexican Adults: A Regression-Based Approach

2025· article· en· W4416392537 on OpenAlexaboutno aff
Lorena Parra‐Rodríguez, Juan Silva‐Pereyra, Sergio Sánchez‐García, Carmen García‐Peña, Juan Francisco Flores-Vázquez, Paloma Roa‐Rojas

Bibliographic record

VenueDiagnostics · 2025
Typearticle
Languageen
FieldMedicine
TopicDementia and Cognitive Impairment Research
Canadian institutionsnot available
Fundersnot available
KeywordsNormativeMontreal Cognitive AssessmentCognitionRaw scoreRaw dataTest (biology)Sample (material)Cognitive Assessment System

Abstract

fetched live from OpenAlex

Background/Objectives: The Montreal Cognitive Assessment (MoCA) is a widely used cognitive screening tool designed to detect cognitive impairment. However, evidence indicates that the original cut-off score of 26 and the one-point correction for low education may not be appropriate across diverse populations. In Latin America, and particularly in Mexico, existing validation studies are scarce and limited by small sample sizes. The objective of this study was to examine the effects of age and education on MoCA performance in Mexican adults and to develop regression-based normative data for more accurate interpretation. Methods: MoCA performance of 2546 cognitively healthy participants aged 18–99 years from two public health institutions in Mexico City was analyzed. Inclusion criteria required preserved cognition, functionality, independence, and absence of conditions directly affecting brain health. The Spanish version 8.1 of the MoCA was administered. Age-adjusted normative values were obtained. Then, regression analyses were applied to generate age- and education-adjusted norms. Results: MoCA total scores correlated negatively with age and positively with education, while sex showed no significant effect. Regression-based norms revealed that identical raw total scores have different normative interpretations depending on age and education. Conclusions: This study provides the first regression-based MoCA norms for Mexican adults, demonstrating that both age and education exert a substantial influence on test performance. These norms enable a more precise, culturally sensitive interpretation than fixed cut-off scores and reduce the risk of misclassification in clinical and research settings.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.735
Threshold uncertainty score0.418

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.388
Teacher spread0.356 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueDiagnosticsSame topicDementia and Cognitive Impairment ResearchFrench-language works237,207