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Record W4416398837 · doi:10.1093/jsxmed/qdaf311.045

(S17) a systemic review exploring the relationship between Varicocele and premature ejaculation

2025· article· en· W4416398837 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueThe Journal of Sexual Medicine · 2025
Typearticle
Languageen
FieldHealth Professions
TopicMale Reproductive Health Studies
Canadian institutionsnot available
Fundersnot available
KeywordsVaricocelePremature ejaculationEjaculationSexual dysfunctionSperm qualityPositive correlationCorrelation

Abstract

fetched live from OpenAlex

Abstract Background Premature ejaculation (PE) is a male sexual dysfunction characterized by ejaculation that always or nearly always occurs prior to or within a short period of vaginal penetration. Recently, a correlation between varicocele and (PE) has been observed sparking an interest in exploring the effect of varicocele repair on the duration of ejaculation. This work is aimed at systemically reviewing the literature to assess the correlation between (PE) and varicocele through (1) exploring the prevalence of PE in patients with varicocele, (2) reporting the effect of varicocelectomy on the duration of ejaculation or (PE) measures, and (3) assessing the quality of studies investigating this relationship. Methods This systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta- Analysis (PRISMA) guidelines. Studies were included if they were original and (1) reported an association between the presence of clinical varicocele and premature ejaculation and/or (2) explored changes in ejaculation latency time after varicocele correction (either by subjective measures or by using objective measurement tools). The quality of the included studies was assessed using the Newcastle-Ottawa Scale (NOS) for non-randomized studies. Results Eight articles met the eligibility criteria and were included in the review. Two of the 8 studies examined the prevalence of (PE) among men with varicocele, reporting a significantly higher prevalence compared to those without varicocele. The remaining 6 studies explored the impact of varicocelectomy on various measures of (PE). Results of these studies were found to be conflicting. Considerable heterogeneity was noted with respect to the methods used in defining (PE) or measuring the outcome of varicocelectomy on ejaculation time. The (NOS) results identified two studies with a score of 8 stars, two studies with 6 stars, one with 5 stars and three with 4 stars. Conclusion (PE) is more prevalent in patients with varicocele in comparison to men without varicocele. Limited evidence suggests that varicocelectomy may be associated with prolongation of ejaculatory time and improvement in (PE). However, further studies are still required before indicating varicocele ligation as a sole treatment modality for patients with (PE).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.008
metaresearch head score (Gemma)0.007
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.398
Threshold uncertainty score0.863

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0080.007
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.331
GPT teacher head0.498
Teacher spread0.167 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it