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Record W4416402891 · doi:10.3389/froh.2025.1701839

The first 1,000 days of life and early childhood caries: closing the global data gap

2025· article· en· W4416402891 on OpenAlexaff
Morẹ́nikẹ́ Oluwátóyìn Foláyan, Balgis Gaffar, Carlos Alberto Feldens, Robert J. Schroth, Francisco Ramos‐Gomez, Jorma I. Virtanen, Hye Won Lee, Abiola Adeniyi, Maha El Tantawi

Bibliographic record

VenueFrontiers in Oral Health · 2025
Typearticle
Languageen
FieldDentistry
TopicDental Health and Care Utilization
Canadian institutionsUniversity of Manitoba
Fundersnot available
KeywordsClosing (real estate)Global healthPublic healthScarcityEarly childhoodData collectionScale (ratio)

Abstract

fetched live from OpenAlex

The first 1,000 days of life represent a critical window for preventing Early Childhood Caries (ECC). However, a significant global data gap obscures the true scale of ECC within this critical period. This review aims to systematically examine the global availability of ECC data for children under 36 months, discuss age-specific prevalence trends, and synthesize evidence to highlight the implications of missing data. A comprehensive analysis of a global dataset reporting ECC prevalence across 193 United Nations member states (2007-2017) was conducted. Analysis of the data was organized by the World Health Organization Region. The analysis revealed a profound data gap: 73.6% of countries had no data for children under 36 months, and only 19.7% had current data. Where data existed, rates approach or exceed 50% in some countries (e.g., Egypt: 69.6%, Mongolia: 47.5%), indicating that ECC is often well-established in the first 1,000 days of life. Significant regional disparities were identified, with the highest burden in the European Region, the Eastern Mediterranean Region, and the Western Pacific Region. Even within regions, there are extreme disparities in prevalence between countries (e.g., Kuwait at 3.0% vs. Egypt at 69.6% in the Middle East; Finland at 0.3% vs. Kazakhstan at 45.0% in Europe). The scarcity of data and high prevalence rates highlight a public oral health problem in infancy. Closing this global data gap is an essential first step to mobilize resources and implement targeted, effective prevention strategies where we can have the greatest impact.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.018
metaresearch head score (Gemma)0.075
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.018
Threshold uncertainty score0.094

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0180.075
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0030.003
Bibliometrics0.0080.010
Science and technology studies0.0010.002
Scholarly communication0.0040.007
Open science0.0020.003
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.324
Teacher spread0.299 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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