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Record W4416421275 · doi:10.1016/j.clinsp.2025.100833

Effects of a moderate combined exercise program on cognitive function, quality of life, and glycemic profile in older adults with type II diabetes mellitus

2025· article· en· W4416421275 on OpenAlexaboutno aff
Matheus Henrique dos Santos Lino, Vanderlei Carneiro da Silva, Marcus Vinicius Grecco, André Luiz de Seixas Soares, Catherine L. Davis, José Maria Soares, Edmund Chada Baracat, Guilherme Carlos Brech, Adriana Machado‐Lima, Júlia María D’Andréa Greve, Angélica Castilho Alonso

Bibliographic record

VenueClinics · 2025
Typearticle
Languageen
FieldMedicine
TopicDiet and metabolism studies
Canadian institutionsnot available
FundersCoordenação de Aperfeiçoamento de Pessoal de Nível Superior
KeywordsGlycemicCognitionFructosamineDiabetes mellitusType 2 Diabetes MellitusRecall

Abstract

fetched live from OpenAlex

BACKGROUND: The risk of developing non-communicable chronic diseases, such as Type 2 Diabetes Mellitus (T2DM), has increased due to factors such as sedentary behavior, the adoption of nutrient-poor dietary patterns, and an increase in population longevity. Regular physical activity has been shown to lower these risks and prevent chronic non-communicable diseases. OBJECTIVE: This study aims to assess how a combined training program affects the Quality of Life (QoL), cognitive function, and glycemic profile of older people with T2DM. METHODS: Forty-three senior citizens participated in this experimental study. The process of assessing the glucose profile involved drawing 20 milliliters of peripheral blood for laboratory examination. The WHOQOL-Old and WHOQOL-Bref questionnaires were used to assess QoL, and the Montreal Cognitive Assessment (MoCA) was used to measure cognitive function. Targeting the main muscular groups, the intervention includes combination training for 12-weeks, twice a week, comprising leg press, calf raises, chest press, rowing, leg curls, and abdominal exercises. There was also thirty minutes of moderate intensity aerobic cycling exercise. RESULTS: After three months of moderate CT, older adults with T2DM showed improvements in fructosamine levels (partial η² = 0.07), indicating a medium effect size. Small effect sizes (partial η² ≈ 0.02-0.04) were observed in QoL domains related to physical, psychological, and environmental well-being. In cognitive function, a significant improvement was found in the abstraction domain (p = 0.031; partial η² = 0.12), with additional small effect sizes in delayed recall (partial η² = 0.04) and orientation (partial η² = 0.04) domains. CONCLUSION: There was a reduction in fructosamine levels and slightly improved QoL in physical, psychological, and environmental domains, with no change in HbA1c or aging-specific QoL. Cognitive function showed improvement in abstraction and small gains in recall and orientation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Non-randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.311
Teacher spread0.297 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNon-randomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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