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Combining implementation and data sciences to accelerate evidence integration into healthcare – ImpleMATE

2025· article· en· W4416430908 on OpenAlexaff
J. Chan, Janna Hastings, Gabriella Tiernan, Jeannie Paterson, Nigel H. Lovell, Luc Betbeder-Matibet, Patrick Kin Man Tung, Débora Lanzeni, Thomasina Donovan, Andrew Milat, Louisa Jorm, Carolyn Mazariego, Chi Zhang, Guillaume Fontaine, Stephanie Best, Georgina Kennedy, Susan Michie, Frank Lin

Bibliographic record

VenueF1000Research · 2025
Typearticle
Languageen
FieldHealth Professions
TopicHealth Policy Implementation Science
Canadian institutionsMcGill UniversityOttawa Hospital
Fundersnot available
KeywordsProcess (computing)Pipeline (software)Health carePlan (archaeology)Data governanceKey (lock)Data integrationCorporate governanceKnowledge translation

Abstract

fetched live from OpenAlex

<ns3:p>Background The translation of research evidence into routine healthcare practice is often slow and inconsistent, even timely implementation can significantly improve patient outcomes. While implementation science offers strategies to close this gap, current approaches are frequently manual, fragmented, and poorly integrated within healthcare systems. To address these challenges, we propose ImpleMATE – an AI-powered implementation science platform designed to streamline implementation efforts. Grounded in the Learning Health System (LHS) model, ImpleMATE aims to establish a continuous, data-driven cycle of learning and improvement in implementation practice. Methods ImpleMATE will be developed through a co-design and co-production approach rooted in human-centred design principles. Development will proceed through four key activities: (1) establishing a data processing pipeline and building an implementation-focused ontology; (2) creating and validating an AI system to extract implementation knowledge, structure the ontology, and support implementation solution delivery; (3) designing an interactive web application to deliver AI-powered decision support and streamline implementation processes; and (4) developing an evaluation framework to assess platform’s effectiveness and plan for national integration. These activities align with three core components of the LHS model: converting data into knowledge, translating knowledge into practice, and feeding implementation process and outcome data back into the system for continuous learning. The platform will be underpinned by strong ethical and governance frameworks to ensure data privacy, transparency, and responsible AI use. Discussion ImpleMATE aims to transform the adoption of evidence-based innovations in healthcare by embedding trustworthy AI into the core of implementation practice. Through the integration of structured ontologies, real-time AI reasoning, and an interactive user interface, the platform will provide tailored solutions to support implementation efforts. Designed as a dynamic learning system, ImpleMATE will evolve with user input and real-world data, offering a scalable, ethically grounded solution to accelerate and enhance implementation across healthcare settings.</ns3:p>

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.015
metaresearch head score (Gemma)0.004
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.337
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0150.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0030.000
Scholarly communication0.0000.001
Open science0.0010.002
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.923
GPT teacher head0.833
Teacher spread0.091 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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