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Record W4416431002 · doi:10.1038/s44172-025-00548-6

Degrees of uncertainty: conformal deep learning for non-invasive core body temperature prediction in extreme environments

2025· article· en· W4416431002 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueCommunications Engineering · 2025
Typearticle
Languageen
FieldMedicine
TopicThermal Regulation in Medicine
Canadian institutionsLaurentian University
Fundersnot available
KeywordsDeep learningConformal mapCore (optical fiber)Wearable computerProbabilistic logicCalibrationWearable technology

Abstract

fetched live from OpenAlex

Accurate estimation of core body temperature (CBT) is essential for physiological monitoring, yet current non-invasive methods lack statistically calibrated uncertainty estimates required for safety-critical use. Here we introduce a conformal deep learning framework for real-time, non-invasive CBT prediction with calibrated uncertainty, demonstrated in high-risk heat-stress environments. Developed from over 140,000 physiological measurements across six operational domains, the model achieves a test error of 0.29 °C, outperforming the widely used ECTemp™ algorithm with a 12-fold improvement in calibrated probabilistic accuracy and statistically valid prediction intervals. Designed for integration with wearable devices, the system uses accessible physiological, demographic, and environmental inputs to support practical, confidence-informed monitoring. A customizable alert engine enables proactive safety interventions based on user-defined thresholds and model confidence. By combining deep learning with conformal prediction, this approach establishes a generalizable foundation for trustworthy, non-invasive physiological monitoring, demonstrated here for CBT under heat stress but applicable to broader safety-critical settings.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.428
Threshold uncertainty score0.441

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.273
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it