MétaCan
Menu
Back to cohort
Record W4416443111 · doi:10.5376/gab.2025.16.0006

Comparative Analysis of Male and Female Tilapia Gonadal Transcriptomes

2025· article· W4416443111 on OpenAlexvenueno aff
Manman Li

Bibliographic record

VenueGenomics and Applied Biology · 2025
Typearticle
Language
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Canadian institutionsnot available
Fundersnot available
KeywordsTranscriptomeGonadTilapiaGeneDevelopment of the gonadsGene expressionGene regulatory networkGamete

Abstract

fetched live from OpenAlex

This study explores the mechanisms of environmental adaptability and reproductive stability of tilapia, analyzes the biological basis of its gonad development and sex differentiation, and provides a theoretical basis for optimizing sex regulation strategies and improving aquaculture benefits. Based on pre-gonadal transcriptomic analysis, this study identified core regulatory genes such as Dmrt1 , Cyp19a1a and Foxl2 , as well as gender-specific RNA expression profiles that affect steroid synthesis and gamete formation. The study revealed the core signaling pathways of gonadal maturation, including the TGF-β/Wnt network for testis development and the BMP cascade reaction for ovarian differentiation. Through the localization of the interaction network and the analysis of the expression trend, the gene synergy mechanism guiding the development of gonads was clarified. This study systematically evaluated the practical value of early gender identification, molecular marker application, and targeted gene editing technologies. By combining the existing technical bottlenecks with future breakthrough directions, a multi-dimensional theoretical framework was constructed for improving the gender control system in tilapia farming.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.424
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.276
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueGenomics and Applied BiologySame topicGenetic and Clinical Aspects of Sex Determination and Chromosomal AbnormalitiesFrench-language works237,207