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Record W4416443126 · doi:10.5376/gab.2025.16.0008

Genomic Insights into Hypoxia Tolerance Mechanisms in Channa spp.

2025· article· W4416443126 on OpenAlexvenueno aff

Bibliographic record

VenueGenomics and Applied Biology · 2025
Typearticle
Language
FieldEnvironmental Science
TopicPhysiological and biochemical adaptations
Canadian institutionsnot available
Fundersnot available
KeywordsTranscriptomeGeneHypoxia (environmental)GenomeHeat shock proteinGene expressionGenomic information

Abstract

fetched live from OpenAlex

The study summarizes the current genomic results on how Channa fish adapt to hypoxia. We performed high-quality genome assembly and transcriptome analysis on Channa asiatica . The results showed that it has more gene families related to oxygen binding and transport. When it is exposed to air, many pathways related to oxidative stress are activated. This shows that it has the genetic ability to adapt to hypoxia and also reveals some of the molecular mechanisms. We also studied gene expression in the liver of Channa striatus  under long-term hypoxia. We found that many genes involved in transcription, translation, signal transduction, electron transport and immune response were activated. Several transcripts related to hypoxia tolerance were also identified, such as heat shock protein 90 and fatty acid binding protein, and we also obtained their complete sequences. These research results provide important genomic and transcriptome resources, which will help us to better understand how Channa fish adapt to low oxygen environments. At the same time, it also lays a foundation for future research on hypoxia tolerance breeding and ecological adaptation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.775
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.208
Teacher spread0.198 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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