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Record W4416443273 · doi:10.5376/be.2025.15.0003

Structural Variation of Chicken Genome: Genetic Basis in Domestication and Evolution

2025· article· W4416443273 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueBiological Evidence · 2025
Typearticle
Language
FieldBiochemistry, Genetics and Molecular Biology
TopicAnimal Genetics and Reproduction
Canadian institutionsnot available
Fundersnot available
KeywordsDomesticationStructural variationTraitAdaptation (eye)Gene duplicationGenetic variationMechanism (biology)GenomeGene

Abstract

fetched live from OpenAlex

The domestic chicken (Gallus gallus domesticus) is one of the most common domestic animals around us. It is widely distributed around the world, closely related to human life, and is an animal with high economic value. In recent years, with the development of high-throughput sequencing technology, scientists have found that the impact of "structural changes" in the genome (such as large changes such as duplication and deletion of gene segments) on the domestication and trait evolution of chickens may be more important than we thought. Starting from the structure of the chicken genome, this article explains the types of variation, detection technology, and its important role in evolution and artificial selection. The article focuses on the origin mechanism of SV, the distribution differences among different chicken species, and its impact on gene expression, phenotype, and domestication traits (such as feather color, comb shape, growth rate, and egg-laying ability). Finally, a specific case, the duplication variation of the TBC1D1 gene region in broilers, is used to explore the mechanism of SV in the rapid growth trait of broilers. At the end of the article, we look forward to the application prospects of emerging technologies such as single-cell analysis, pan-genome construction, and genomic selection in SV research and poultry breeding. Structural variation is an important genetic basis in the process of domesticated chickens. In-depth research on the mechanisms and functions contained therein will help reveal the genetic nature of complex traits and promote the development of precision breeding.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.841
Threshold uncertainty score0.727

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.279
Teacher spread0.257 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it