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Record W4416504201 · doi:10.1016/j.nexus.2025.100582

Bioprocess strategies for enhancing lipid content in microalgae to improve biofuel production

2025· article· en· W4416504201 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueEnergy Nexus · 2025
Typearticle
Languageen
FieldEnergy
TopicAlgal biology and biofuel production
Canadian institutionsInnovation Cluster (Canada)
FundersScience and Technology Research Partnership for Sustainable DevelopmentJapan Science and Technology AgencyUniversitas PadjadjaranJICA Research InstituteLembaga Pengelola Dana PendidikanJapan International Cooperation Agency
KeywordsBiofuelBioprocessSustainabilityLife-cycle assessmentProductivityRenewable energyEnvironmental impact assessmentProduction (economics)Bioenergy

Abstract

fetched live from OpenAlex

Microalgae have emerged as promising candidates for third- and fourth-generation biofuels due to their ability to efficiently fix CO₂, accumulate high lipid content, and adapt to extreme environments with minimal resource input. This review critically examines recent advances across the entire microalgae biofuel production chain. It highlights key species with high lipid productivity and strong environmental tolerance, including those capable of thriving in wastewater, saline, and acidic conditions. The review further synthesizes current strategies for enhancing lipid accumulation, encompassing both genetic interventions and environmental manipulations. Innovations in post-harvest processing—such as integrated fermentation, thermochemical conversion, and anaerobic digestion—have also demonstrated improvements in overall biofuel yield and energy recovery. Despite these advancements, challenges related to scalability, cost-effectiveness, and industrial CO₂ integration remain significant barriers to commercialization. This review underscores the importance of continued efforts in strain engineering, direct CO₂ utilization from industrial emissions, and life cycle sustainability assessments, while also highlighting emerging opportunities through systems biology, AI-driven modeling, smart biorefineries, and circular bioeconomy integration to enhance the overall viability and environmental performance of microalgae biofuels in meeting future global energy demands.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.073
Threshold uncertainty score0.740

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.255
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it