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Cerebrovascular regulation during increases in systemic blood flow and systemic vascular resistance

2025· article· en· W4416506077 on OpenAlexaff
Emma H.M. Torn, Bas van Zaane, Niels P. van der Kaaij, Lisette M. Vernooij, Jan-Folkert Heida, Wilton A. van Klei, Rogier V. Immink

Bibliographic record

VenueJournal of Applied Physiology · 2025
Typearticle
Languageen
FieldMedicine
TopicTraumatic Brain Injury and Neurovascular Disturbances
Canadian institutionsToronto General HospitalUniversity of TorontoUniversity Health Network
Fundersnot available
KeywordsVascular resistanceBlood pressureCerebral blood flowCerebral perfusion pressureMiddle cerebral arteryBlood flowVasoconstrictionCardiopulmonary bypass

Abstract

fetched live from OpenAlex

Elevating blood pressure by increasing cardiac blood flow ([Formula: see text]) or by increasing systemic vascular resistance (SVR) results in a comparable increase in middle cerebral artery blood velocity. In contrast, although frontal cerebral lobe oxygenation increased with increasing [Formula: see text], it decreased with increasing SVR. This difference was less pronounced when [Formula: see text] was kept constant, suggesting that part of the decrease may be attributed to an SVR-induced decrease in [Formula: see text].

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.216
Teacher spread0.210 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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