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Record W4416538864 · doi:10.7417/ct.2025.5302

Impact of Dyslipidemia, Cardiovascular Disease, Smoking, and Stroke Type by Brain Imaging on Pneumonia Risk in ICU Stroke Patients: A Cross-Sectional Observational Study.

2025· article· en· W4416538864 on OpenAlexaff
Naglaa Youssef, M Abdellatif, Abdelsattar M. Omar, Mona Abdel Mageed, Ahmed Essmat, Neghae Mawla, Hebatalla I. Ahmed, Ahmed Ali Ali Assem, T Abualkasem, A.A.A. Darwish, Hanem Elrazek, Mahmoud Ahmed Arfa, Ahmed Mohamed Abdallah Beshir, Irini Youssef, N Gouda, Riad Salem, O Safwat, Hanaa Kamel Elmahdy, Maha Hassan, A Metwally, Mohamed Abdelrahman, M Gerges, A R Ali, Ahmed Roushdy, Waseem Ahmed, Shaimaa Mostafa Abdelmoniem

Bibliographic record

VenuePubMed · 2025
Typearticle
Languageen
FieldMedicine
TopicAcute Ischemic Stroke Management
Canadian institutionsDalhousie University
Fundersnot available
KeywordsObservational studyPneumoniaStroke (engine)Ischemic strokeNeuroimagingProspective cohort studyRisk factorMulticenter study

Abstract

fetched live from OpenAlex

Background: Stroke-associated pneumonia (SAP) is an associated condition after stroke and is strongly related to prolonged hospitalization and a high mortality rate. While comorbidities are often assumed to influence pneumonia risk, their role remains uncertain across stroke subtypes. Objective: To identify predictors of pneumonia in ischemic and hemorrhagic stroke patients, with emphasis on age, sex, and common vascular comorbidities. Methods: We analyzed 300 stroke patients who underwent a tertiary care hospitalization, including 237 ischemic and 63 hemorrhagic cases. Demographic and clinical variables, such as sex, hypertension, ischemic heart disease, smoking, and dyslipidemia, were assessed. Pneumonia occurrence was the primary outcome. Chi-square tests and binary logistic regression were used to identify independent predictors. Results: Pneumonia developed in 55% of ischemic stroke patients and 17.5% of those with hemorrhagic stroke. In ischemic stroke, age was the only independent predictor of pneumonia (OR: 1.01; 95% CI: 1.00-1.03; p = 0.042). Sex and comorbidities showed no significant associations. In hemorrhagic stroke, none of the evaluated variables predicted pneumonia. Conclusion: Post-stroke pneumonia was more common in ischemic than hemorrhagic stroke. Age was the sole independent predictor among ischemic patients, while traditionally assumed comorbidities were not significant. Preventive strategies should focus on older ischemic patients, incorporating systematic aspiration screening and targeted pulmonary care. A bigger prospective multicenter data evaluation is needed to validate and expand these findings.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.003
Meta-epidemiology (narrow)0.0000.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.294
Teacher spread0.269 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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Same venuePubMed→Same topicAcute Ischemic Stroke Management→French-language works237,207→