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Record W4416540705 · doi:10.1016/j.resplu.2025.101156

Comparison of foreign body airway obstruction interventions among laypersons: A simulation-based, crossover, randomized controlled trial

2025· article· en· W4416540705 on OpenAlexafffund
Cody Dunne, Nojan Mannani, Julia Cirone, Adam Cheng, Ian E. Blanchard, Jayna Holroyd‐Leduc, Todd Wilson, Khara Sauro, Andrew D. McRae

Bibliographic record

VenueResuscitation Plus · 2025
Typearticle
Languageen
FieldMedicine
TopicForeign Body Medical Cases
Canadian institutionsAlberta Health ServicesUniversity of Calgary
FundersCanadian Institutes of Health ResearchCanadian Association of Emergency Physicians
KeywordsRandomized controlled trialAirwayPsychological interventionAirway obstructionForeign body

Abstract

fetched live from OpenAlex

Background: Foreign body airway obstruction (FBAO) is a life-threatening emergency where rapid bystander intervention is essential. Suction-based airway clearance devices like Dechoker (DC) and LifeVac (LV) are marketed alternatives to abdominal thrusts (AT), but their efficacy among laypersons is unclear. We aimed to determine which intervention (AT, DC or LV) has the greatest efficacy for FBAO relief by laypersons. Methods: We conducted a simulation-based, crossover, randomized controlled trial. Adult laypersons received standardized in-person instruction on AT, DC, and LV, then responded to three simulated FBAO events on an adult mannequin. A mixed-effects logistic regression model estimated the odds ratios (OR) of FBAO relief at one minute (primary outcome) and four minutes (secondary), adjusted for carryover effects. Skill retention was evaluated 90-120 days later without retraining. Results: Of 139 participants, 132 were eligible and randomized. Median age was 39 years (IQR: 26-56), and 66 % were female. At one minute, FBAO relief occurred in 86 % (LV), 62 % (DC), and 49 % (AT) of cases. LV had greater odds of relief than AT (OR = 12.4 [95 %CI 5.6-27.2]) and DC (OR = 5.8 [95 % CI 2.8-12.1]). Compared with AT, DC also had greater odds of relief (OR = 2.1 [95 %CI 1.2-3.8]). At four minutes, results were similar. During follow-up testing, LV remained superior to AT (OR = 97.7 [95 %CI 6.3-1549]), while DC did not. Conclusion: After brief training, LifeVac was superior to abdominal thrusts and Dechoker for simulated FBAO relief among laypersons. Research evaluating LifeVac's safety and effectiveness in a controlled clinical setting is now needed. Trial registration: ClinicalTrials.gov Identifier: NCT06227234.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.008
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.028

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0050.008
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0050.004
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.002
Open science0.0020.001
Research integrity0.0030.003
Insufficient payload (model declined to judge)0.0070.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.387
Teacher spread0.350 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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