Serum Procalcitonin Values Relate to Disease Activity in Patients with Inflammatory Bowel Diseases
Bibliographic record
Abstract
Objective: In inflammatory bowel disease (IBD) patients, the correlation between disease activity and serum procalcitonin (SPCT) values remains elusive. By using a number of clinical and laboratory phenotypes of disease activity in conjunction with the degree of mucosal inflammation in patients with ulcerative colitis (UC), we sought to determine whether the blood SPCT levels of IBD patients could be useful as a biomarker. Methods: This retrospective case-control study was conducted with 132 UC patients, 83 Crohn’s disease (CD) patients, and 72 healthy controls (HCs). In UC, endoscopic and clinical activity were identified using the Mayo Clinical Scoring System (MCS), and the histological activity index (HAI) was calculated using the Truelove and Richards technique. The Crohn's disease activity index (CDAI) of CD patients was calculated. The Montreal classification was preferred for determining disease localization in IBD patients. Results: The median SPCT levels were higher in the UC and CD patients compared to the HC (0.07 vs 0.26 vs 0.03 ng/ml, respectively, p
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".