MétaCan
Menu
Back to cohort
Record W4416554587 · doi:10.2106/jbjs.oa.25.00253

Heterotopic Ossification in Cementless Trochanteric Sparing Short Stem Total Hip Arthroplasty

2025· article· en· W4416554587 on OpenAlexaboutno aff
Ali Soltani Farsani, Pouya Tabatabaei Irani, Mohammadreza Razzaghof, Mohammad Poursalehian, Seyed Mohammad Javad Mortazavi

Bibliographic record

VenueJBJS Open Access · 2025
Typearticle
Languageen
FieldMedicine
TopicOrthopaedic implants and arthroplasty
Canadian institutionsnot available
Fundersnot available
KeywordsHeterotopic ossificationTotal hip arthroplastyTotal hip replacementArthroplastyHeterotopic boneProsthesis

Abstract

fetched live from OpenAlex

Background: Heterotopic ossification (HO) is a common complication of total hip arthroplasty (THA), which can adversely affect patient satisfaction. Although the direct anterior approach (DAA) has been associated with lower rates of HO, the exact clinical impact of even low-grade ossification following DAA THA remains underreported. We aimed to assess the clinical impact of HO in DAA THA and identify demographics and implant-related risk factors. Methods: A retrospective single-center cohort study of 348 hips treated via DAA THA with a cementless short stem between January 2011 and December 2021 was performed. HO was graded at ≥12 months using the Brooker classification on standardized anteroposterior radiographs. The Harris Hip Score (HHS), the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and the Visual Analogue Scale (VAS) were assessed at a mean of 4.3 years of follow-up. Comparative analyses and multivariable logistic regression were performed to identify independent predictors of HO. Results: HO occurred in 18.1% of hips: Brooker grade I in 12.4%, II in 3.0%, and III in 3.0%; no grade IV lesions developed. At final follow-up, patients without HO had significantly better outcomes compared with those with HO (all p < 0.001). When stratified by severity, even low-grade HO (Brooker I-II) was associated with significantly worse WOMAC (p = 0.023) and HHS (p < 0.001) compared with the non-HO group. Although VAS pain was higher in the low-grade group, the difference did not reach statistical significance (p = 0.084). On multivariable analysis, independent implant-related risk factors included use of the Continuum acetabular cup (odds ratio [OR] 2.10; p = 0.014), each additional millimeter of cup diameter (OR 1.16; p = 0.003), and longer femoral neck length (OR 2.06; p = 0.006). Conclusions: HO was observed in nearly one-fifth of hips, and even low-grade ossification was associated with significantly worse mid-term functional outcomes. Cup design, size, and neck length were identified as significant, modifiable predictors of HO risk. Careful implant selection may help reduce the incidence of HO and enhance postoperative function. Level of Evidence: Therapeutic Level II. See Instructions for Authors for a complete description of levels of evidence.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.074
GPT teacher head0.390
Teacher spread0.317 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueJBJS Open AccessSame topicOrthopaedic implants and arthroplastyFrench-language works237,207