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Record W4416555385 · doi:10.1038/s41598-025-28614-1

Air pollution and cognitive function: the potential protective effect of physical activity

2025· article· en· W4416555385 on OpenAlexaboutno aff
Lin Zhu, Mingjun Zou

Bibliographic record

VenueScientific Reports · 2025
Typearticle
Languageen
FieldEnvironmental Science
TopicAir Quality and Health Impacts
Canadian institutionsnot available
Fundersnot available
KeywordsCognitionAir pollutionPollutantInterquartile rangeAir pollutantsParticulatesPollutionCognitive testMontreal Cognitive Assessment

Abstract

fetched live from OpenAlex

Physical activity (PA) may mitigate pollution‐related cognitive decline while concurrently increasing individuals’ exposure to harmful pollutants. Data were obtained from the 2018 China Health and Retirement Longitudinal Study (CHARLS), comprising 17,734 participants aged 45 years or older. Information regarding particulate matter (PM 1 , PM 2.5 , and PM 10 ), nitrogen dioxide (NO 2 ), sulfur dioxide (SO 2 ) and ozone (O 3 ) was sourced from the China High Air Pollutants (CHAP) database. The assessment of cognitive function was carried out following the approach utilized in the Health and Retirement Study (HRS). The impact of air pollutants on cognitive function was estimated using the two-stage least squares method, with the ventilation coefficient serving as an instrumental variable. The results indicated that all air pollutants were significantly associated with cognitive function. An interquartile range (IQR) increase in PM 1 , PM 2.5 , PM 10 , NO 2 , SO 2 , and O 3 corresponded to decreases in cognitive function of −0.45 (95% CI: −0.76, −0.13), −0.43 (95% CI: −0.74, −0.13), −0.53 (95% CI: −0.90, −0.16), −0.57 (95% CI: −0.96, −0.17), −0.47 (95% CI: −0.80, −0.14), and −1.06 (95% CI: −1.81, −0.31), respectively. Further stratified analyses revealed that higher levels of PA significantly moderated the association between air pollution and cognitive function, suggesting a potential protective effect. The level of PA was found to modify this association of pollution and cognitive function, with higher PA levels seemingly alleviating the adverse cognitive effects of air pollution. These findings underscore the importance of policies that simultaneously target pollution reduction and promote PA to safeguard cognitive health.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.016
Threshold uncertainty score0.032

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.290
Teacher spread0.278 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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