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Record W4416561516 · doi:10.1016/j.burnso.2025.100435

12 Years of ablative fractional CO2 laser Practice: Logistics, lessons and evolving model of care

2025· article· en· W4416561516 on OpenAlexaff
Natalia Ziolkowski, Fiona Wood, Suzanne Rea, Inge Spronk, Dale W. Edgar, Helen Douglas

Bibliographic record

VenueBurns Open · 2025
Typearticle
Languageen
FieldMedicine
TopicDermatologic Treatments and Research
Canadian institutionsMcMaster UniversityHamilton Health SciencesHamilton General Hospital
FundersNederlandse Brandwonden Stichting
KeywordsAblative caseRetrospective cohort studyScarsCohortLaser therapyHypertrophic scarsLaser treatment

Abstract

fetched live from OpenAlex

• Ablative fractional CO 2 laser (AFCO 2 L) services improve equity of access to scar treatment. • AFCO 2 L service resulted in reduced burn scar operative reconstructive cases. • Younger, female patients more likely to receive AFCO 2 L. • Patients with slower healing burns more likely to receive surgery and AFCO 2 L. Ablative fractional CO 2 lasers (AFCO 2 L) have been shown to improve burn hypertrophic scars significantly. In this paper we describe the journey of setting up the laser service for burns patients, considerations in patient selection, treatment algorithms, and lessons learned. This study is a retrospective cohort study including all patients who received AFCO 2 L at the Western Australian (WA) Statewide Adult Burn Unit since the start of the program in 2013–2024. Descriptive statistics present the number, timing and settings of AFCO 2 L events, as well as patient, injury, and treatment characteristics. Further, the profile of patients who underwent laser treatment was compared to those who did not, during the study period. Since the introduction of the AFCO2L, a total of 4005 laser sessions involving 837 burns patients has been completed in WA. The majority were performed as an outpatient (66 %), with the proportion and total numbers increasing with time to 2021. Compared to those not receiving laser for their scars, AFCO2L was more likely applied to younger (p < 0.0001), female (p < 0.0001) patients with higher %TBSA burns (p < 0.0001) involving multiple anatomic areas (p = 0.001), more often requiring surgery (p < 0.0001) and longer times to heal (p < 0.0001). In 2013, 100 % of all lasers were provided as an inpatient, under general anesthetic with an average age of scar > 5000 days. By 2023/4, only 18 % required an inpatient stay and the average age of scar was 111 days. The SABU team evolved AFCO 2 L therapy into the model of care over time to achieve earlier, more equitable delivery of laser treatments to 80 % of patients as outpatients, supported by extensive multidisciplinary team involvement.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.702
Threshold uncertainty score0.161

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.074
GPT teacher head0.432
Teacher spread0.359 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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