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Record W4416580372 · doi:10.1016/j.sapharm.2025.11.003

Effects of pharmacist prescribing on health-related outcomes in secondary care compared with medical prescribing or no treatment: A systematic review

2025· article· en· W4416580372 on OpenAlexaboutno aff
A. Akintunde, Ajlin Karaxhija, Raisa Laaksonen

Bibliographic record

VenueResearch in Social and Administrative Pharmacy · 2025
Typearticle
Languageen
FieldMedicine
TopicPharmaceutical Practices and Patient Outcomes
Canadian institutionsnot available
Fundersnot available
KeywordsPharmacistSecondary careMedical prescriptionMEDLINEDrug Utilization ReviewSystematic reviewPrimary care

Abstract

fetched live from OpenAlex

BACKGROUND: Pharmacist prescribing has gained momentum over the years and is currently utilised in Brazil, Canada, New Zealand, Poland, South Africa, United Kingdom (UK), and the United States of America (USA). While pharmacist prescribing has been associated with symptom improvement, reduced prescribing error rates, medication omissions, and improved medication access, the effects of pharmacist prescribing in secondary care have not been previously evaluated. OBJECTIVES: This systematic review aimed to assess the effects of pharmacist prescribing on health-related outcomes in secondary care. METHODS: MEDLINE, Cochrane, CINAHL, Scopus, and Web of Science Core Collection databases were searched for studies published in English from database inception to October 3, 2024. Studies were included if the intervention was pharmacist prescribing and the outcomes were health-related and measurable. Narrative synthesis of the outcomes from included studies was conducted. RESULTS: A total of 21 studies from five countries (Australia, Egypt, Hong Kong, UK, USA) were included. Pharmacist prescribing significantly improved disease management, reduced the number of hospital revisits, improved blood pressure control, international normalised ratio control and decreased the number of adverse events when compared to medical prescribing. The evidence further suggests that the healthcare costs per patient per month, median cost of treatment, inpatient hospitalisations and emergency department admissions were significantly lower when pharmacists prescribed medicines. The evidence was low to moderate quality. CONCLUSION: This systematic review provides evidence that pharmacist prescribing has a positive effect on therapeutic outcomes, and that pharmacist prescribing is comparable or better than medical prescribing in secondary care.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.009
metaresearch head score (Gemma)0.042
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.011
Threshold uncertainty score0.046

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0090.042
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0110.011
Bibliometrics0.0080.009
Science and technology studies0.0010.001
Scholarly communication0.0030.002
Open science0.0010.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.383
GPT teacher head0.567
Teacher spread0.183 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2025
Admission routes1
Has abstractyes

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