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Record W4416599729 · doi:10.1186/s12982-025-01107-2

Knowledge, attitudes and perceptions of healthcare workers on antimicrobial stewardship and antibiotic use: a nationwide multi-center study in Bangladesh

2025· article· en· W4416599729 on OpenAlexaff
Faisal Chowdhury, Md. Abu Sayem, Md. Akram Hossain, Md. Abdus Salam, Ayesha Ahmed Khan, Abu Sadat Mohammad Nurunnabi, Tanveer Ahmed, Kakali Halder, Sabrina Monsur, Md. Mizanur Rahaman, Ummey Shahnaz Parvin, Mahbub‐Ul Alam, S. M. Selimuzzaman, Fahmida Khanam, Sourav Nath, Md. Muid Sakib Mim, Zahin Zeima

Bibliographic record

VenueDiscover Public Health · 2025
Typearticle
Languageen
FieldImmunology and Microbiology
TopicAntibiotic Use and Resistance
Canadian institutionsPublic Health Ontario
Fundersnot available
KeywordsAntimicrobial stewardshipHealth careInfection controlAntibiotic resistanceMedical prescriptionPublic healthStewardship (theology)Perception

Abstract

fetched live from OpenAlex

Antimicrobial resistance (AMR) disproportionately affects low and middle income countries (LMICs) including Bangladesh, driven by poorly implemented infection prevention and control (IPC) and misuse of antimicrobials. Robust Antimicrobial Stewardship (AMS) programs mitigate this risk by optimizing prescribing to best-practice standards. This study aimed to assess healthcare workers’ (HCWs) knowledge, attitude and perception (KAP) toward AMS. An online questionnaire was shared via IPC Alliance BD to different health-related institutes and hospitals, inviting voluntary and anonymous participation of HCWs on KAP between January to March 2025. A total of 721 participants from 171 hospitals and institutes (78 public and 93 private), comprising 29% medical officers or equivalent, 29% nurses, 28% professors or equivalent and 14% administrative staff and other roles were enrolled. The average age was 36 years, and females accounted for 54% of respondents. Overall, 43% of respondents were familiar with the term AMS, reached through various sources. Only 11% received AMS training, and 18% had access to standard treatment guidelines. Despite 66% reporting availability of culture and sensitivity (C/S) testing, only 26% routinely recommended C/S and 15% shared an antibiogram. Empirical therapy predominated (> 94%), with a 60% preference for broad-spectrum agents. However, 67% believed rational use and proper IPC can reduce AMR. Knowledge, attitudes, and perceptions varied significantly by age, gender, and education (P < 0.05). Antimicrobial resistance in Bangladesh necessitates strengthened laboratory capacity, expanded public awareness, and improved healthcare worker’s KAP via structured training and continuous monitoring, with robust antimicrobial stewardship as the operational benchmark.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.010
Threshold uncertainty score0.654

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.034
GPT teacher head0.338
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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