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Record W4416602306 · doi:10.1021/acs.jcim.5c01946

HlightReaxMD: A Machine Learning-Augmented Multiscale Analysis Framework for Radiation Chemistry Dynamics and Damage Prediction

2025· article· en· W4416602306 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJournal of Chemical Information and Modeling · 2025
Typearticle
Languageen
FieldMaterials Science
TopicMachine Learning in Materials Science
Canadian institutionsInstitute of Particle Physics
FundersPostdoctoral Research Foundation of ChinaNatural Science Basic Research Program of Shaanxi ProvinceShaanxi Provincial Science and Technology DepartmentChina Postdoctoral Science Foundation
KeywordsReaxFFMicroscale chemistryMolecular dynamicsCascadeChemical reactionProcess (computing)TrajectoryIrradiationCollision

Abstract

fetched live from OpenAlex

Molecular dynamics (MD) simulations are currently widely used to study large-scale displacement cascades based on massive simulation trajectories. However, when the irradiation process involves the complex chemical reactions, effectively analyzing and extracting features from these data becomes a challenge. Here, we introduce a new cross-platform toolkit, HlightReaxMD, designed to directly obtain information about the irradiation damage process and chemical reactions from MD trajectories and further achieve the prediction of irradiation damage. The analysis tools in HlightReaxMD include chemical reaction analysis and calculation of reaction kinetic parameters, analysis of the collision cascade process, and calculation of necessary physicochemical properties. HlightReaxMD supports the analysis of all elements used in reactive force fields by reading ReaxFF potential file parameters and provides an automated solution for tracking atomic-scale collision events and analyzing chemical reaction mechanisms through constructing cascade trees and reaction network paths. A machine learning-driven model using the analysis results has been included in HlightReaxMD, which can predict irradiation damage by considering various factors, rather than relying solely on the Norgett-Robinson-Torrens displacements per atom (NRT-dpa) model. It enables researchers to automatically obtain dynamic processes and reaction information from atomic to microscale defects from terabyte-level trajectory data. Thus, HlightReaxMD can promote systematic research on irradiation effects in materials science.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.464
Threshold uncertainty score0.329

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.266
Teacher spread0.259 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it