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Record W4416625104 · doi:10.1097/mcc.0000000000001345

Safe spontaneous breathing with helmet noninvasive ventilation in acute hypoxemic respiratory failure

2025· article· en· W4416625104 on OpenAlexaff
Tommaso Rosà, Luca S. Menga, Bruno L. Ferreyro, Domenico Luca Grieco, Massimo Antonelli

Bibliographic record

VenueCurrent Opinion in Critical Care · 2025
Typearticle
Languageen
FieldMedicine
TopicRespiratory Support and Mechanisms
Canadian institutionsSinai Health SystemUniversity of TorontoUniversity Health NetworkSt. Michael's Hospital
Fundersnot available
KeywordsNoninvasive ventilationBreathingVentilation (architecture)Clinical trialMEDLINEAcute respiratory failure

Abstract

fetched live from OpenAlex

PURPOSE OF REVIEW: Helmet noninvasive ventilation (NIV) has gained attention for the management of hypoxemic patients, owing to physiological and potential clinical benefits. We summarize the recent advances on the topic. RECENT FINDINGS: Compared to facemasks, helmets facilitate application of higher positive end-expiratory pressure (PEEP) for prolonged treatments: this improves oxygenation and may mitigate injurious inflation patterns related to lung heterogeneity. The large, highly compliant interface reduces ventilator triggering performance, causing pressure support to be partially out of phase with patient's inspiratory effort; however, it allows patients to breathe from the internal air reservoir, resulting in formally asynchronous breaths that may help attenuate surges in lung stress and tidal volume without causing flow starvation. Through physiological monitoring, ventilator settings can be individualized to modulate inspiratory effort while limiting increases in dynamic transpulmonary driving pressure and tidal volume. SUMMARY: Helmet NIV may offer a valuable strategy for noninvasive management of hypoxemic patients, particularly when applied early, for prolonged periods, and with settings aimed at minimizing injurious inflation in moderate-to-severe (PaO 2 /FiO 2 < 200 mmHg) cases. Interface peculiarities affecting patient-ventilator interaction may constitute key differences with facemask NIV for prevention of injurious inflation patterns. Ongoing trials will clarify whether these physiological advantages improve clinical outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.002
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.067
GPT teacher head0.400
Teacher spread0.333 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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