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Integration of a serious video game to positive expiratory pressure respiratory physiotherapy in pediatric patients with cystic fibrosis: a prospective study

2025· article· W4416635181 on OpenAlexaff
Olivia Victoria CERUTTI-MONTEVENTI, Fabio Balli, Tiberius Brastaviceanu, Yannick Gervais, Alexandre Larocque, Sarah Wilhelmy, The Thanh-Diem Nguyen, Sze Man Tse

Bibliographic record

Venuenot available
Typearticle
Language
FieldMedicine
TopicCystic Fibrosis Research Advances
Canadian institutionsCentre Hospitalier Universitaire Sainte-Justine
Fundersnot available
KeywordsProspective cohort studyPostural drainageCystic fibrosisVideo gameContinuous positive airway pressureAsthmaPhoneTest (biology)

Abstract

fetched live from OpenAlex

Background: PEP therapy is a cornerstone of the physiotherapeutic treatment in cystic fibrosis (CF), supporting its impaired airway clearance. Multiple studies report poor adherence to the PEP (~50%), mainly due to its time-consuming/monotonous aspect. Technologic advances (e.g. serious games) in health have the potential to change the management of chronic diseases through education and by improving adherence. We will evaluate if this is applicable in children with CF. Aims: 1) to evaluate if a serious game can improve adherence to PEP therapy in children with CF, 2) to further co-create this game with them/their families. Methods: 1-year monocentric, prospective study in the CF clinic at the CHUSJ. Inclusion criteria: age 6-17 years, diagnosed with CF, using PEP therapy for ≥6 months. Thirty participants were enrolled and were able to take home an electronic pressure sensor that follows the number of breaths/repetitions/pressures is connected to the usual PEP setup, enabling them to play a game through their breath and test is over a period of 3 months. Families were regularly contacted for a 15-minutes phone call to gather their feedback, ensuring continuous co-creation with the participants (game usability, visuals and relevance). Results: This innovative serious game was well accepted in our study population. Results show increased adherence to the PEP treatment in comparison to their reported adherence pre-game. Ultimately, this may lead to an improvement in the patients’ lung health due to the better mucus clearing achieved through a more regularly performed PEP treatment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.017

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.307
Teacher spread0.301 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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