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Impact of patient engagement tool on PAP therapy outcomes

2025· article· W4416636008 on OpenAlexaff
Jean‐Louis Pépin, Holger Woehrle, Suyog More, Caleb Woodford, Ankit Ghildiyal, Melike Deger

Bibliographic record

Venuenot available
Typearticle
Language
FieldBiochemistry, Genetics and Molecular Biology
TopicProtease and Inhibitor Mechanisms
Canadian institutionsGreenfield Research (Canada)
Fundersnot available
KeywordsResidualConcordanceLeakRetrospective cohort studyWeightingPatient satisfaction

Abstract

fetched live from OpenAlex

Background: A patient engagement tool incorporating subjective feedback from the first 30 days was developed to support PAP therapy. This study evaluated the impact of PET engagement on PAP usage, discontinuation, residual AHI, and mask leak at 365 days vs. no engagement. Methods: This retrospective analysis included 63,873 connected PAP users (age 51.8 ± 12.7 years; 27.4% female) across Europe. Patients were grouped by level of engagement in the first 30 days: Full (baseline + all additional check-ins), Partial (Baseline and/or First 30 Days) and no engagement. Inverse probability weighting adjusted for age, gender, country, therapy mode, usage, leak rates and residual AHI. Average usage, residual AHI, mask leak, and CPAP termination at 365 days were compared. Results: At 1 year, the fully engaged group showed higher average usage (5.21 ± 2.32 vs. 4.51 ± 2.71hrs/day; <0.001) and a greater percentage of patients averaging ≥4 hrs/night (72.7% vs. 60.7%, p<0.001) compared to the not engaged group. Mask leak was lower (p=0.004), while residual AHI was similar (p=0.518). 1 year CPAP termination risk was 46% lower (RR: 0.56) (p<0.001) for the fully engaged group compared to the not engaged group. Conclusion: Patients fully engaged with PET in the first 30 days of PAP therapy show better adherence and lower termination rates in the first year than non-engaged patients. These findings underscore digital tool's potential to improve long-term PAP therapy outcomes. erj;66/suppl_69/PA2869/F1 F1 F1

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.011
metaresearch head score (Gemma)0.039
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.011
Threshold uncertainty score0.057

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0110.039
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.002
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.298
Teacher spread0.286 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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