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Every Cough Matters: Six Months of Monitoring Reveal New Insights into Air Pollution's Impact on Interstitial Lung Disease's Cough.

2025· article· W4416636895 on OpenAlexaff
Umberto Zanini, Hunter Vander Linden, Giovanni Ferrara

Bibliographic record

Venuenot available
Typearticle
Language
FieldMedicine
TopicInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Canadian institutionsUniversity of AlbertaConcordia University of Edmonton
Fundersnot available
KeywordsCohortInterstitial lung diseaseRespiratory systemAir pollutionAir pollutantsCohort studyProspective cohort studyRespiratory disease

Abstract

fetched live from OpenAlex

Introduction: Cough is a key symptom of interstitial lung disease (ILD), impacting disease progression. While air pollution triggers respiratory symptoms, its role in ILD-related coughing is unknown. This study uses wearable devices to monitor how air pollution affects ILD's cough. Methods: This is a single, prospective cohort study involving ILD patients. Cough was recorded over six months using the ADAMM-RSM™ wearable device. PM2.5, ozone, and wind speed levels were collected from air monitoring stations. Cough and pollutant spikes were defined using established thresholds, and temporal associations were analyzed. Results: Six patients were enrolled, yielding 24,371 cough episodes over 1,170 monitoring days. PM2.5 levels showed the strongest association with increased cough frequency 7 to 14 days post-exposure, peaking on day eight (OR: 2.045; 95% CI: 1.393-2.695). Ozone spikes started an acute increase in coughing within the first 5 days, followed by a gradual return to baseline by day ten. Elevated wind speeds were associated with a reduction in cough. erj;66/suppl_69/PA4015/F1 F1 F1 Discussion: This six-month study highlights the impact of air pollution on cough in patients with ILD. Wearable devices offer valuable insights into environmental triggers, suggesting that air quality assessments should be considered into clinical protocols. Further multicenter studies are needed to validate these initial findings.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.021

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0060.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.288
Teacher spread0.281 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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