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Multimodal Neuropsychological Rehabilitation of Patients with Post-COVID Cognitive Impairment

2025· article· W4416665002 on OpenAlexaboutno aff
Anna Kutkova

Bibliographic record

VenuePsikhiatriya · 2025
Typearticle
Language
FieldMedicine
TopicLong-Term Effects of COVID-19
Canadian institutionsnot available
FundersAcademy of Military Medical Sciences
KeywordsNeurorehabilitationRehabilitationNeuropsychologyVerbal fluency testCognitive rehabilitation therapyAnxietyCognitionNeuropsychological assessment

Abstract

fetched live from OpenAlex

Background: post-COVID cognitive impairment is an important medical and social problem. Many studies focus on the analysis of the characteristics of cognitive impairment after infection, but neurorehabilitation issues are rarely considered. The aim was to study the effectiveness of combined use of neuropsychological correction and rhythmic magnetic stimulation (rTMS) in the rehabilitation of patients with post-COVID cognitive impairment. Patients and Methods: two groups of 20 people with postCOVID cognitive impairment were compared: group 1 underwent rehabilitation using a multimodal method, group 2 — according to the standard program. The areas of rTMS stimulation were selected based on high-quality neuropsychological diagnostics, which made it possible to identify and form the patient’s neuropsychological profile. The correction program was based on the identified neuropsychological profile and developed individually for each patient. The Montreal Cognitive Assessment, Frontal Area Dysfunction Battery, Clock Drawing Test, Semantic Verbal Fluency Test, 10-Word Learning, Symbolic-Digit Coding Test, Subjective Asthenia Inventory (MFI-20), and Hospital Anxiety and Depression Scale (HADS) were used to assess the state of higher mental functions. Results: after correction, significant differences were found in the MoCA, 10-Word Learning, Symbolic-Digit Coding, and MFI-20 scales, with higher scores in group 1. Comparative analysis showed significant differences in score dynamics between the groups, with group 1 demonstrating better results. Conclusions: multimodal neuropsychological rehabilitation in combination with rTMS demonstrates significantly higher results compared to standard rehabilitation protocols established in the order of the Ministry of Health of the Russian Federation dated July 31, 2020 No. 788n “On approval of the Procedure for organizing medical rehabilitation of adults” [1], as well as with clinical recommendations presented on the website of the Union of Rehabilitation Specialists of Russia [2–4].

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.009
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.017
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.009
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.293
Teacher spread0.288 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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