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Record W4416665728 · doi:10.1007/s40520-025-03238-7

Relationships between pain, physical activity and sleep quality among older adults with radiographic knee osteoarthritis: findings from the Hertfordshire Cohort Study

2025· article· en· W4416665728 on OpenAlexaboutno aff
Fiona Kirkham-Wilson, Leo D. Westbury, Gregorio Bevilacqua, Faidra Laskou, Nicholas R. Fuggle, Elaine Dennison

Bibliographic record

VenueAging Clinical and Experimental Research · 2025
Typearticle
Languageen
FieldMedicine
TopicOsteoarthritis Treatment and Mechanisms
Canadian institutionsnot available
FundersMedical Research CouncilNational Institute for Health and Care Research
KeywordsPhysical activityCohort studySleep qualityCohortSleep (system call)Knee painRadiographySleep disorder

Abstract

fetched live from OpenAlex

AIMS: To determine if the relationship between joint pain and sleep quality among individuals with osteoarthritis (OA) differs according to physical activity level among older adults. METHODS: 169 community-dwelling older adults in the UK Hertfordshire Cohort Study (aged 71-80) with radiographic knee OA completed a questionnaire. This included: the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC); the Pittsburgh Sleep Quality Index (PSQI); the Longitudinal Aging Study Amsterdam Physical Activity Questionnaire; and the Hospital Anxiety and Depression (HAD) Scale. Logistic regression was used to examine the WOMAC knee pain score in relation to having poor sleep quality (PSQI > 5) with adjustment for sex, age, and anxiety and depression scores; analyses were performed with and without stratification by physical activity category (bottom sex-specific tertile vs. not). RESULTS: Knee pain prevalence (WOMAC pain score > 0) was 40.7% among men and 46.6% among women; 37.0% of men and 50.0% of women reported poor sleep quality (PSQI > 5). Higher WOMAC pain scores were related to increased risk of poor sleep quality; odds ratio (95% CI) per unit increase in pain score: 1.15 (1.01,1.32), p = 0.038). Relationships were similar across physical activity levels. CONCLUSIONS: Relationships between joint pain and poor sleep quality among older adults with radiographic knee OA were similar, regardless of physical activity level. Our results highlight the high prevalence of both sleep disturbance and significant knee pain in this group, illustrating the need to consider supportive measures as appropriate in this population.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.074
Threshold uncertainty score0.556

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.067
GPT teacher head0.418
Teacher spread0.351 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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