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Record W4416666591 · doi:10.1055/a-2753-9092

Epidemiology of Functional Neurological Disorder: The Clinical Spectrum

2025· article· en· W4416666591 on OpenAlexaff
Emma K. Woo, Gabriela S. Gilmour

Bibliographic record

VenueSeminars in Neurology · 2025
Typearticle
Languageen
FieldMedicine
TopicPsychosomatic Disorders and Their Treatments
Canadian institutionsHotchkiss Brain InstituteUniversity of Calgary
Fundersnot available
KeywordsEpidemiologyIncidence (geometry)Socioeconomic statusNeurological disorderFunctional impairmentComorbidityHealth careMEDLINE

Abstract

fetched live from OpenAlex

Abstract: Functional neurological disorder (FND) is a prevalent, neuropsychiatric condition characterized by symptoms of impaired motor, sensory, cognitive, or perceptual systems. This study reviews the incidence, prevalence, demographic factors, risk factors, comorbidities, prognosis, and economic impact of FND and its subtypes. FND affects individuals across the lifespan and is more common in women, with socioeconomic and cultural factors also playing critical roles. FND is frequently comorbid with other functional syndromes, psychiatric and neurological disorders. Incidence estimates range from 10 to 16 per 100,000, with prevalence estimates between 79 and 144 per 100,000. Prognosis is poor without early intervention, with long diagnostic delays contributing to chronic symptoms and disability. FND accounts for significant healthcare utilization and economic burden. Evidently, there is a clear need for standardized diagnostic approaches and interdisciplinary collaboration to improve epidemiological accuracy and clinical outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.009
Threshold uncertainty score0.019

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0020.002
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.040
GPT teacher head0.357
Teacher spread0.318 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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