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Record W4416671537 · doi:10.1007/s10433-025-00892-8

Associations between life satisfaction and hope with cognitive function and decline over 13 years: findings from the Whitehall II study

2025· article· en· W4416671537 on OpenAlexfundno aff
Amber John, Aysha Mohamed Rafik Patel, Roopal Desai, Emily C Willroth, Natalie L. Marchant, Harriet Demnitz‐King, Barbara Woodward‐Carlton, Dorina Cadar, David Bartrés‐Faz, Rob Saunders, G Bell, Aida Suárez González, Darya Gaysina, Marcus Richards, Joshua Stott

Bibliographic record

VenueEuropean Journal of Ageing · 2025
Typearticle
Languageen
FieldPsychology
TopicOptimism, Hope, and Well-being
Canadian institutionsnot available
FundersNational Heart, Lung, and Blood InstituteNational Institute on AgingEconomic and Social Research CouncilMedical Research CouncilNational Institutes of HealthAgencia Estatal de InvestigaciónDementias Platform UKAlzheimer's SocietyInstitució Catalana de Recerca i Estudis AvançatsBritish Heart FoundationAlzheimer Society
KeywordsVerbal fluency testCognitionCognitive declineDementiaAssociation (psychology)Inductive reasoningTest (biology)FluencyCognitive testLife satisfaction

Abstract

fetched live from OpenAlex

Evidence indicates an association between wellbeing (e.g., purpose in life) and cognition over time. However, wellbeing is a multifaceted construct, and most research has focused on purpose in life and positive affect, with less research on other aspects of wellbeing. The aim of this study was to test associations between life satisfaction (LS) and hope with cognitive function and decline. Data were used from Whitehall II, a longitudinal cohort study of people employed by the British Civil Service. Measures of LS and hope were available at Wave 7, and cognitive function (phonemic/semantic verbal fluency, memory and inductive reasoning) at Waves 7, 9, 11, and 12. Linear mixed models were fitted to test associations between LS and hope with cognitive function and decline over 13 years. LS was positively associated with baseline cognitive function (overall cognition, verbal fluency, memory, and inductive reasoning) cross-sectionally but not with decline over time. Hope was positively associated with baseline overall cognition, phonemic fluency and inductive reasoning (but not semantic fluency or memory). Hope was associated with slower decline in inductive reasoning over 13 years. Findings contribute to better understanding of the temporal relationship between wellbeing and cognitive function from middle to older age. People with higher hope show lower baseline cognition and slower decline in inductive reasoning. People with lower LS show lower initial cognitive function and this difference is maintained over time. Although decline is not steeper for those with lower LS, they may reach the threshold for dementia earlier than those with higher LS.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.014
Threshold uncertainty score0.029

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.276
Teacher spread0.259 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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